Biomaterial Database

Effect of hydrocortisone acetate on interrenal cells in the normal and hypophysectomized catfish, Heteropneustes fossilis, (Bloch). 1976

B R Belurkar, and D K Belsare

The interrenal gland of the Heteropneustes fossilis occupies three fourth area of the kidney and shows two types of cells histologically. The cells are arranged as cortical strands. Hypophysectomy resulted in regressive changes in the interrenal gland, as seen from the significant reduction in the nuclear diameter within fifteen days. A single injection of hydrocortisone brought about further reduction in the size of interrenal cell and the nuclear diameter in the hypophysectomized animals, but not in the intact fish. It is concluded that the amount of hydrocortisone added was sufficient to cause reduced functioning of the interrenal gland in the absence of ACTH.

UI	MeSH Term	Description	Entries
D007016	Hypophysectomy	Surgical removal or destruction of the hypophysis, or pituitary gland. (Dorland, 28th ed)	Hypophysectomies
D007401	Interrenal Gland	Structures in fishes homologous to the cortical tissue of the mammalian adrenal gland; they are in close proximity to or imbedded in the kidney.	Gland, Interrenal,Glands, Interrenal,Interrenal Glands
D010913	Pituitary-Adrenal System	The interactions between the anterior pituitary and adrenal glands, in which corticotropin (ACTH) stimulates the adrenal cortex and adrenal cortical hormones suppress the production of corticotropin by the anterior pituitary.	Pituitary Adrenal System,Pituitary-Adrenal Systems,System, Pituitary-Adrenal,Systems, Pituitary-Adrenal
D005260	Female		Females
D005399	Fishes	A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D006854	Hydrocortisone	The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.	Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol
D000311	Adrenal Glands	A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.	Adrenal Gland,Gland, Adrenal,Glands, Adrenal
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia