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Changes in the peripheral blood leukocyte count and in the ability of lymphocytes to transform in response to phytohemagglutinin were studied in healthy volunteers undergoing prolonged enflurane or halothane anesthesia without coincident surgical operation. Anesthesia was associated with a modest leukocytosis that persisted into the first post-anesthesic day, primarily due to an influx of neutrophils into the circulation. There was no significant alteration, either during or following anesthesia, in the ability of the volunteers' lymphocytes to transform in response to phytohemagglutinin when compared with either preanesthetic values or unanesthetized controls. Depression of lymphocyte transformation does not appear to follow prolonged enflurane or halothane anesthesia in the absence of a surgical procedure.
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
April 1977,
Anesthesiology,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
August 1985,
Anesthesiology,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
January 1980,
The Cornell veterinarian,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
June 1980,
Annals of clinical research,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
April 1980,
Anesthesia and analgesia,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
June 1978,
L'union medicale du Canada,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
April 1979,
Journal of applied physiology: respiratory, environmental and exercise physiology,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
January 1991,
Annals of the New York Academy of Sciences,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
December 1978,
Anesthesiology,
P G Duncan, and
B F Cullen, and
R Calverly, and
N T Smith, and
E I Eger, and
R Bone
January 1982,
Anesthesiology,
