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Renal vein thrombosis can occur as a complication of nephrotic syndrome. We present the case of a young man with nephrotic syndrome caused by minimal change disease who developed acute inferior vena cava and left renal vein thrombosis. He was treated initially with intravenous heparin. Because of the persistence of severe left flank pain and gross hematuria, local infusion of recombinant tissue plasminogen activator was tried, with resolution of thrombi and subsidence of symptoms. Functional preservation of the involved kidney is good, as indicated by Tc-99m DMSA scan (involved kidney, 47.4%; uninvolved kidney, 52.6%). Anticoagulation is usually recommended as the treatment of choice in renal vein thrombosis. We believe that in cases with critical presentations, such as bilateral involvement, extension into inferior vena cava, acute renal failure, pulmonary embolism or severe flank pain, thrombolytic therapy should be considered as a second-line treatment if good response is not obtained with heparin.
K K Lam, and
C C Lui
May 1991,
Chest,
K K Lam, and
C C Lui
February 1964,
Zeitschrift fur Urologie,
K K Lam, and
C C Lui
January 1991,
Klinische Padiatrie,
K K Lam, and
C C Lui
October 2017,
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation,
K K Lam, and
C C Lui
October 2002,
Nephron,
K K Lam, and
C C Lui
December 1993,
European journal of pediatrics,
K K Lam, and
C C Lui
January 1992,
Lakartidningen,
K K Lam, and
C C Lui
May 1998,
Urology,
K K Lam, and
C C Lui
June 2001,
Surgical neurology,
K K Lam, and
C C Lui
January 1990,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
