Urethritis. Diagnosis of nongonococcal urethritis. 1998

A Stary
Outpatients Center for Infectious Venero-Dermatological Diseases and Fungal Infections, Vienna, Austria.

Nongonococcal urethritis (NGU) frequently occurs in men after infection of the lower genital tract with a genital pathogen and is mostly associate with complaint of a scanty, thin discharge and urinary symptoms. Management of NGU includes clinical examination, microbiological diagnosis of genital pathogens, and efficient treatment as well as contact tracing. Diagnosis, especially of the Chlamydia trachomatis, the most frequent cause of NGU, has improved by using amplification assays for the detection of DNA or rRNA. These new methods have the advantage of a higher sensitivity especially for specimens with a low number of infectious agents. In addition, they enable the use of urine as a noninvasive specimen type.

UI MeSH Term Description Entries
D008297 Male Males
D002690 Chlamydia Infections Infections with bacteria of the genus CHLAMYDIA. Infections, Chlamydia,Chlamydia Infection,Infection, Chlamydia
D002692 Chlamydia trachomatis Type species of CHLAMYDIA causing a variety of ocular and urogenital diseases.
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D004269 DNA, Bacterial Deoxyribonucleic acid that makes up the genetic material of bacteria. Bacterial DNA
D005832 Genital Diseases, Male Pathological processes involving the male reproductive tract (GENITALIA, MALE). Male Genital Diseases,Disease, Male Genital,Diseases, Male Genital,Genital Disease, Male,Male Genital Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001437 Bacteriuria The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection. Bacteriurias
D012335 RNA, Ribosomal The most abundant form of RNA. Together with proteins, it forms the ribosomes, playing a structural role and also a role in ribosomal binding of mRNA and tRNAs. Individual chains are conventionally designated by their sedimentation coefficients. In eukaryotes, four large chains exist, synthesized in the nucleolus and constituting about 50% of the ribosome. (Dorland, 28th ed) Ribosomal RNA,15S RNA,RNA, 15S
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity

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