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By means of a modified and simplified surgical and implantation technique, standardized values for visually evoked potentials (EP) from 7 brain structures (caudate nucleus, posterior hypothalamus, mesencephalic reticular formation, intra-laminar thalamic nuclei, amygdala, dorsal hippocampus and visual cortex) are obtained. The importance of a careful selection of the animal material, constant test conditions and the selection of test parameters as a prerequisite for the assessment of psychotropic drugs is emphasized and discussed. As an example of the specific influence on visually evoked potentials in the above named brain structures, the effects of haloperidol and amytriptyline on latencies and amplitudes of the individual parameters of EPs are described. It is assumed that the method described can be of great assistance for investigation and classification of newly developed substances.
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
January 1983,
Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
January 1964,
Activitas nervosa superior,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
May 1962,
Journal of neurophysiology,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
March 1956,
Journal of neurophysiology,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
August 1965,
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
June 1973,
Brain research,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
January 1974,
Neurologia i neurochirurgia polska,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
January 1971,
Neuropharmacology,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
August 1960,
Electroencephalography and clinical neurophysiology,
B Pollock, and
P R Bock, and
A M Fuchs, and
R Lohaus
September 1961,
Ceskoslovenska neurologie,
