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The concentration of selenium in human red cells was measured by a fluorometric determination method after wet digestion of the biological material. In the red cells from the same blood samples the activity of the selenoenzyem glutathione peroxidase (EC 1.11.1.9) was determined with tertiary butyl hydroperoxide as acceptor substrate. The results show that only 10% of the total selenium content of human red cells is fixed to the enzyme. No correlation between the enzyme activity and the selenium concentration could be found. On the basis of these results can be presumed that the protective effect of selenium in glutathione peroxidase against oxidant damage of cells is not the only biological function of this element.
K Schmidt, and
W Heller
February 1982,
Clinical chemistry,
K Schmidt, and
W Heller
January 1983,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
K Schmidt, and
W Heller
January 1979,
Archiv fur experimentelle Veterinarmedizin,
K Schmidt, and
W Heller
January 1976,
The British veterinary journal,
K Schmidt, and
W Heller
April 1975,
The Veterinary record,
K Schmidt, and
W Heller
June 1982,
Biological trace element research,
K Schmidt, and
W Heller
July 1987,
The American journal of clinical nutrition,
K Schmidt, and
W Heller
January 1993,
Biological trace element research,
K Schmidt, and
W Heller
July 1995,
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS),
K Schmidt, and
W Heller
April 1988,
Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete,
