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Blood samples from 580 African leprosy patients living in Rhodesia have been phenotyped for the plasma cholinesterase variants. The Africans have been grouped according to country of origin and tribal affiliation. We have found no individual with an Ea1 gene and are unable to resolve the contradictory evidence for an association between this gene and leprosy. The frequency of the Ef1 gene is higher than that usually found in Caucasian populations, being 0.046 in lepromatous leprosy patients and similar to the 0.056 found in healthy African controls. In tuberculoid leprosy patients the frequency is, however, significantly lower at 0.019. On the other hand, the frequency of the C5+ variant is essentially the same for the tuberculoid leprosy patients and the healthy controls (4%) while for the lepromatous leprosy patients it is about 7% approaching the 10-15% found in many Caucasian populations.
M Whittaker, and
R F Lowe, and
B P Ellis
January 1951,
East African medical journal,
M Whittaker, and
R F Lowe, and
B P Ellis
February 1975,
The Australasian nurses journal,
M Whittaker, and
R F Lowe, and
B P Ellis
September 1986,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
M Whittaker, and
R F Lowe, and
B P Ellis
July 1987,
Rinsho byori. The Japanese journal of clinical pathology,
M Whittaker, and
R F Lowe, and
B P Ellis
August 1979,
Masui. The Japanese journal of anesthesiology,
M Whittaker, and
R F Lowe, and
B P Ellis
January 1990,
Haematologia,
M Whittaker, and
R F Lowe, and
B P Ellis
January 1978,
Acta anaesthesiologica Scandinavica,
M Whittaker, and
R F Lowe, and
B P Ellis
January 1978,
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association,
M Whittaker, and
R F Lowe, and
B P Ellis
August 1959,
The Central African journal of medicine,
M Whittaker, and
R F Lowe, and
B P Ellis
October 1953,
Leprosy review,
