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Coagulation studies were performed on 128 babies who were premature or who had respiratory distress syndrome (RDS). Forty-four babies were found to have abnormal coagulation parameters. Twenty-one were treated with plasma coagulation factors II, VII, IX and X (PPSB), and of these six died from intraventricular haemorrhage (IVH). Twenty-two did not have PPSB treatment and four died from IVH. In 84 babies in whom coagulation studies gave normal results only one baby died from IVH. The combination of RDS and abnormal coagulation produced a high-risk group to IVH and treatment with PPSB did not reduce the incidence of IVH. It is postulated that prevention of IVH lies in early and effective treatment of RDS.
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
October 1976,
The Medical journal of Australia,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
August 1976,
The Medical journal of Australia,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
July 1984,
Irish medical journal,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
January 2003,
Revista de neurologia,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
September 1974,
Archives of disease in childhood,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
August 1967,
Developmental medicine and child neurology,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
June 1979,
Archives of disease in childhood,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
January 1983,
Ciba Foundation symposium,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
June 1964,
Singapore medical journal,
J M Gupta, and
H Starr, and
P Fincher, and
P R Lam-Po-Tang
April 1983,
Lancet (London, England),
