Biomaterial Database

[Holmes-Adie syndrome. Clinical case]. 1998

A C Rodríguez-Barrionuevo, and A Herrero-Hernández, and L Vázquez-Martín

Servicio de Neuropediatría, Hospital Materno-Infantil Carlos Haya, Málaga, España.

BACKGROUND The Adie tonic pupil is an intrinsic, isolated and benign ophthalmoplegia producing defective accommodation and anisocoria. The affectation is unilateral in the 90% of cases and can appear at any age. If associated to patellar tendinous reflexes abolition, constitutes Holmes-Adie syndrome. METHODS We present a 6 years old girl. She suffered a right temporal trauma with cephalea and vomiting for a few hours. After two months, she presented right mydriasis. There were no familiar antecedents. After a year evolution, she has not presented clinical changes. CONCLUSIONS We comment the process's physiopathology.

UI	MeSH Term	Description	Entries
D012025	Reflex, Pupillary	Constriction of the pupil in response to light stimulation of the retina. It refers also to any reflex involving the iris, with resultant alteration of the diameter of the pupil. (Cline et al., Dictionary of Visual Science, 4th ed)	Pupillary Reflex
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000270	Adie Syndrome	A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)	Holmes-Adie Syndrome,Adie's Syndrome,Poorly Reacting Pupils,Holmes Adie Syndrome,Poorly Reacting Pupil,Pupil, Poorly Reacting,Pupils, Poorly Reacting,Syndrome, Adie,Syndrome, Adie's,Syndrome, Holmes-Adie
D015875	Anisocoria	Unequal pupil size, which may represent a benign physiologic variant or a manifestation of disease. Pathologic anisocoria reflects an abnormality in the musculature of the iris (IRIS DISEASES) or in the parasympathetic or sympathetic pathways that innervate the pupil. Physiologic anisocoria refers to an asymmetry of pupil diameter, usually less than 2mm, that is not associated with disease.	Anisocoria, Physiologic,Pupil Diameter Unequal,Pupillary Size Inequality,Inequality, Pupillary Size,Physiologic Anisocoria