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The hepatotoxic effect of 2,4-dichlorophenoxyacetic acid (2,4-D) was investigated. Ultrastructural changes were evaluated in transmission electron microscope. The experiment used 60 male Wistar rats divided into two groups: I--control-18 animals and II--42 animals which received chemically pure 2,4-D acid by gastric gavage in a dose of 200 mg/kg b.w. The animals were sacrificed after 12, 24, 48 hours and 4, 10 and 30 days of the experiment. The results obtained indicate that the administration of 2,4-D acid to rats in a dose inducing acute intoxication leads to ultrastructural changes in the liver, which suggest nonspecific reversible adaptative-type damage to parenchymal cells. The changes observed indicate disorders in energetic processes in hepatocytes and are morphological exponents of detoxicative processes there.
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
October 1996,
Veterinary and human toxicology,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
October 1994,
Veterinary and human toxicology,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
April 1998,
Poultry science,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
January 1993,
Annals of the Medical University, Bialystok, Poland = Roczniki Akademii Medycznej w Bialymstoku,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
January 2002,
Roczniki Akademii Medycznej w Bialymstoku (1995),
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
June 1975,
Environmental research,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
March 1985,
Experimental neurology,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
January 1988,
Patologia polska,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
August 2003,
Xenobiotica; the fate of foreign compounds in biological systems,
M Sulik, and
W Kisielewski, and
B Szynaka, and
A Kemona, and
M Sulkowska, and
A Sulik, and
M Baltaziak
September 1985,
Journal of the neurological sciences,
