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The entry of amoxicillin and ampicillin into cerebrospinal fluid (CSF) of humans was studied in the absence of meningeal inflammation. Twelve volunteers received 33 mg of amoxicillin per kg intravenously over 30 min and nine volunteers received 33 mg of ampicillin per kg. The CSF specimens were sampled at 1, 2, and 4 h after the beginning of the infusion. Blood samples were obtained at the end of the infusion and at 45, 60, 90, 120, 180, and 240 min after the beginning of the infusion. Amoxicillin and ampicillin were both detected in the CSF. Ampicillin tended to give higher CSF levels than amoxicillin, although the difference was small. Serum concentrations of ampicillin equaled those of amoxicillin.
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
June 1977,
Antimicrobial agents and chemotherapy,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
January 1979,
Reviews of infectious diseases,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
December 1978,
Antimicrobial agents and chemotherapy,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
January 1981,
Archivio per le scienze mediche,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
October 1980,
British journal of clinical pharmacology,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
September 1980,
American heart journal,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
May 1957,
Journal of neurology, neurosurgery, and psychiatry,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
June 1974,
The Journal of infectious diseases,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
January 1983,
Antimicrobial agents and chemotherapy,
N Clumeck, and
J P Thys, and
R Vanhoof, and
M P Vanderlinden, and
J P Butzler, and
E Yourassowsky
May 1966,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
