Biomaterial Database

Penetration of the laser light into the skin in vitro. 1999

H Kolárová, and D Ditrichová, and J Wagner

Center of Molecular Biology and Medicine, Department of Medical Biophysics, Medical Faculty, Palacký University, Olomouc, Czech Republic. kol@tunw.upol.cz

OBJECTIVE Knowledge of the optical parameters of the skin is important for all kinds of phototherapy. We analyzed penetration of laser light and proved different optical properties of in vitro specimens of normal skin and granular tissue from skin ulcers. METHODS An He-Ne laser (lambda = 632.8 nm, output 50 mW) and a semiconductor laser (lambda = 675 nm, output 21 mW) were used. The distribution of laser radiation was detected by a CCD camera and evaluated by the image analysis software DIPS. RESULTS Transmittance in granular tissue was about 2.5 times higher than that in normal skin. In the thickest skin sample (2 cm), approximately 0.3% of He-Ne laser and 2.1% of semiconductor laser light penetrated. CONCLUSIONS The results demonstrate the percentage of incident light penetrating the individual skin layers in different localizations on the skin surface, which is a decisive factor for the selection of the radiation dose.

UI	MeSH Term	Description	Entries
D007834	Lasers	An optical source that emits photons in a coherent beam. Light Amplification by Stimulated Emission of Radiation (LASER) is brought about using devices that transform light of varying frequencies into a single intense, nearly nondivergent beam of monochromatic radiation. Lasers operate in the infrared, visible, ultraviolet, or X-ray regions of the spectrum.	Masers,Continuous Wave Lasers,Pulsed Lasers,Q-Switched Lasers,Continuous Wave Laser,Laser,Laser, Continuous Wave,Laser, Pulsed,Laser, Q-Switched,Lasers, Continuous Wave,Lasers, Pulsed,Lasers, Q-Switched,Maser,Pulsed Laser,Q Switched Lasers,Q-Switched Laser
D008297	Male		Males
D010789	Phototherapy	Treatment of disease by exposure to light, especially by variously concentrated light rays or specific wavelengths.	Blue Light Therapy,Blue-light Therapy,Light Therapy,Photoradiation Therapy,Red Light Phototherapy,Therapy, Photoradiation,Blue Light Therapies,Blue-light Therapies,Light Phototherapies, Red,Light Phototherapy, Red,Light Therapies,Light Therapies, Blue,Light Therapy, Blue,Photoradiation Therapies,Phototherapies,Phototherapies, Red Light,Phototherapy, Red Light,Red Light Phototherapies,Therapies, Blue Light,Therapies, Blue-light,Therapies, Light,Therapies, Photoradiation,Therapy, Blue Light,Therapy, Blue-light,Therapy, Light
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000042	Absorption	The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D012542	Scattering, Radiation	The diversion of RADIATION (thermal, electromagnetic, or nuclear) from its original path as a result of interactions or collisions with atoms, molecules, or larger particles in the atmosphere or other media. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Radiation Scattering,Radiation Scatterings,Scatterings, Radiation
D012867	Skin	The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012883	Skin Ulcer	An ULCER of the skin and underlying tissues.	Skin Ulcers,Ulcer, Skin,Ulcers, Skin