[Antibody prevalence against astrovirus according to age groups]. 1999

S Kobayashi, and M Kobayashi, and K Araki, and T Shinozaki, and Y Yanagawa
Department of Pediatrics, Teikyo University School of Medicine.

A study on the prevalence of antibodies against human astrovirus serotype 1 (HAstV-1) and 2 (HAstV-2) was carried out in 170 serum samples obtained from different age groups in Tokyo and Saitama, Japan. Prevalence of specific IgG antibodies to both HAstVs showed decreasing tendency after birth and reached a minimum at the 3-5 months age group. Then, prevalence of antibodies to both serotypes increased after 6 months old, and nearly reach to 100% by the third year of life. The antibody titer to both HAstVs in sera revealed same pattern of antibody prevalence. The sera collected during epidemic season between January and June, had more higher titer of antibody to HAstVs than sera of non-epidemic season between July and December. Our results indicate that the infection of astrovirus in community may be more frequently than previous reports, and infection mainly occur in the 6-11 months age group.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007564 Japan A country in eastern Asia, island chain between the North Pacific Ocean and the Sea of Japan, east of the Korean Peninsula. The capital is Tokyo. Bonin Islands
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D000914 Antibodies, Viral Immunoglobulins produced in response to VIRAL ANTIGENS. Viral Antibodies
D001257 Mamastrovirus A genus of small, circular RNA viruses in the family ASTROVIRIDAE. They cause GASTROENTERITIS and are found in the stools of several vertebrates including humans. Transmission is by the fecal-oral route and there are at least eight human serotypes. The type species is Human astrovirus. Human astrovirus,Human astroviruses,Mamastroviruses,astroviruses, Human

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