BIOMAT Database Logo BIOMAT Database Logo

Angiogenesis does not correlate with prognosis or expression of vascular endothelial growth factor in synovial sarcomas. 1999

S Kawauchi, and T Fukuda, and M Tsuneyoshi
Department of Pathology, National Kyushu Cancer Centre, Fukuoka, Japan.

To investigate the significance of tumour angiogenesis in synovial sarcoma on prognosis, we analysed the correlation between microvessel density (MVD) and various clinicopathological factors or immunohistochemical expression of vascular endothelial growth factor (VEGF) in 54 primary and recurrent synovial sarcomas. MVD in synovial sarcomas did not correlate with prognosis or VEGF expression. Furthermore, VEGF expression in synovial sarcomas did not have any prognostic value on overall survival. Our results indicate that angiogenesis does not play an important role in metastasis of synovial sarcoma and overall survival. Angiogenesis in synovial sarcoma may be controlled by angiogenesis activators other than VEGF.

UI MeSH Term Description Entries
D008222 Lymphokines Soluble protein factors generated by activated lymphocytes that affect other cells, primarily those involved in cellular immunity. Lymphocyte Mediators,Mediators, Lymphocyte
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009389 Neovascularization, Pathologic A pathologic process consisting of the proliferation of blood vessels in abnormal tissues or in abnormal positions. Angiogenesis, Pathologic,Angiogenesis, Pathological,Neovascularization, Pathological,Pathologic Angiogenesis,Pathologic Neovascularization,Pathological Angiogenesis,Pathological Neovascularization
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

S Kawauchi, and T Fukuda, and M Tsuneyoshi
Expression of vascular endothelial growth factor in cerebellar hemangioblastomas does not correlate with tumor angiogenesis.
October 1998, Cancer letters,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Immunohistochemical expression of vascular endothelial growth factor (VEGF) does not correlate with microvessel density in renal cell carcinoma.
January 2007, Neoplasma,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Expression of vascular endothelial growth factor in thoracic sarcomas.
May 2001, The Annals of thoracic surgery,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Vascular endothelial growth factor: angiogenesis, atherogenesis or both?
December 2001, Journal of the American College of Cardiology,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Expression of p53 and vascular endothelial growth factor associated with tumor angiogenesis and prognosis in gastric cancer.
January 1998, Oncology,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia.
August 1995, Journal of the National Cancer Institute,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Vascular endothelial growth factor and its receptor correlate with angiogenesis and survival in pulmonary adenocarcinoma.
January 1997, Anticancer research,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Vascular endothelial growth factor expression coincides with coronary vasculogenesis and angiogenesis.
May 1999, Developmental dynamics : an official publication of the American Association of Anatomists,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
Genetic variation of vascular endothelial growth factor pathway does not correlate with the severity of retinopathy of prematurity.
April 2011, Journal of perinatology : official journal of the California Perinatal Association,
S Kawauchi, and T Fukuda, and M Tsuneyoshi
CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression.
October 2014, Cell death & disease,
Copied contents to your clipboard!