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In a double-blind study of 283 patients (140 given iodamide and 143 diatrizoate), meglumine iodamide 24% produced a significantly greater degree of opacification than meglumine diatrizoate 30% (P less than 0.01 to P less than 0.001) in the renal calyces during the early phase of drip infusion pyelography. The agents were infused at a dose of 4.5 ml/kg, up to a maximum volume of 300 ml, over a period of about 10 min. The incidence and nature of laboratory abnormalities and clinical adverse reactions produced by the drugs were similar. No severe reactions occurred. The apparent superiority of the iodamide solution in the early stage of excretion, despite its lower iodine content, may be due to the partial secretion of iodamide by the renal tubules, as observed in other studies.
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
May 1985,
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A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
January 1974,
Zhonghua yi xue za zhi,
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
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S Ulreich
January 1973,
Polski przeglad radiologii i medycyny nuklearnej,
A H Robbins, and
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G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
December 1970,
Hinyokika kiyo. Acta urologica Japonica,
A H Robbins, and
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C E Putman, and
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S Ulreich
September 1968,
Rinsho hoshasen. Clinical radiography,
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
February 1977,
AJR. American journal of roentgenology,
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
January 1973,
Minerva urologica,
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
January 1973,
Radiologia diagnostica,
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
March 1970,
The Journal of urology,
A H Robbins, and
A T Rosenfield, and
N F Pizzolato, and
G A Irwin, and
C E Putman, and
S G Gerzof, and
S Ulreich
December 1968,
The Ohio State medical journal,
