Developmental changes of distortion product and transient evoked otoacoustic emissions in different age groups. 2000

K Kon, and M Inagaki, and M Kaga
Department of Developmental Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, Ichikawa, Japan.

The developmental changes of distortion product otoacoustic emissions (DPOAEs) and transient evoked otoacoustic emissions (TEOAEs) were evaluated in 275 normal subjects aged from 1 month to 39 years. The DP-grams showed an M-shaped pattern with peaks at 1587 Hz and 5042 Hz for all age groups. In subjects younger than 3 years, low frequency DPOAEs did not rise above the noise floor. The DP levels at high frequency (5042 Hz) did not change much from infancy to young adulthood (12.9-16.5 dB SPL), however, those at low and middle frequency significantly decreased with age. Total echo power (TEP) of TEOAE was greatest in early infancy, decreased rapidly before 6-7 years old, and then decreased gradually (TEP = 16.6 - 1.9 X ln (age)). Wave reproducibility was constant across age. The frequency area peak power (FAPP) to middle and high frequency sounds changed little with age, however, FAPP at low frequency sounds dramatically increased with age. FAPP at 5000 Hz was relatively depressed levels at each age. The TEOAE value was more prominent at middle and low frequencies while DPOAE was predominant at high frequencies. These two measurements may reflect different functions of outer hair cells in the developing cochlea.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D001299 Audiometry The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds. Audiometries
D001306 Auditory Pathways NEURAL PATHWAYS and connections within the CENTRAL NERVOUS SYSTEM, beginning at the hair cells of the ORGAN OF CORTI, continuing along the eighth cranial nerve, and terminating at the AUDITORY CORTEX. Auditory Pathway,Pathway, Auditory,Pathways, Auditory

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