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A modification of the histochemical method for myosin ATPase was used to determine the myofibril complement, mean myofibril size and myofibrillar packing of defined muscle fibre types in rat skeletal muscle. Fast muscle fibres (Types IIA and IIB) were found to have smaller myofibrils and a lower packing density than slower (Type I) fibres. These findings were discussed with respect to their relevance in estimations of muscle strength from histological and histochemical preparations of muscle cross-sections.
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