-transparent.png){kind=logo}
The role of thyrotropin-releasing hormone (TRH) in the secretion of TSH from the anterior pituitary was investigated in rats by active and passive immunization with TRH. The plasma TSH response to propylthiouracil (PTU) in TRH-bovine serum albumin (BSA)-immunized rats was significantly lower than that of BSA-immunized or non-immunized rats. Similarly, the increased plasma TSH level following PTU treatment was significantly suppressed after iv injection of antiserum to TRH. However, the decline in plasma TSH levels was not complete. The results of the present study indicate, at least in part, the physiological significance of endogenous TRH in the regulation of pituitary TSH secretion.
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
March 1978,
Endocrinology,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
October 1994,
Journal of affective disorders,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
January 1977,
Neuroendocrinology,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
September 1977,
The American journal of physiology,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
March 1981,
Clinica chimica acta; international journal of clinical chemistry,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
January 1977,
Panminerva medica,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
January 2000,
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
January 1978,
Annales d'endocrinologie,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
October 1977,
Revista clinica espanola,
M Mori, and
K Wakabayashi, and
K Ohshima, and
Y Shimomura, and
H Fukuda, and
I Kobayashi
January 1976,
La Ricerca in clinica e in laboratorio,
