Biomaterial Database

Introduction: pramipexole: a novel dopamine agonist for the treatment of Parkinson's disease. 2000

J G de Yebenes

Department of Neurology, Fundacion Jimenez Diaz, Facultad de Medicina, Universidad Autonoma de Madrid, Madrid, Spain.

UI	MeSH Term	Description	Entries
D010300	Parkinson Disease	A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)	Idiopathic Parkinson Disease,Lewy Body Parkinson Disease,Paralysis Agitans,Primary Parkinsonism,Idiopathic Parkinson's Disease,Lewy Body Parkinson's Disease,Parkinson Disease, Idiopathic,Parkinson's Disease,Parkinson's Disease, Idiopathic,Parkinson's Disease, Lewy Body,Parkinsonism, Primary
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077487	Pramipexole	A benzothiazole derivative and dopamine agonist with antioxidant properties that is used in the treatment of PARKINSON DISEASE and RESTLESS LEGS SYNDROME.	2-Amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole,2-Amino-6-propylaminotetrahydrobenzothiazole,4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazole-diamine,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine dihydrochloride monohydrate,Mirapex,Pramipexol,Pramipexol Dihydrobromide, (+-)-isomer,Pramipexol Dihydrochloride, (S)-isomer,Pramipexol, (+-)-isomer,Pramipexole Dihydrochloride,Pramipexole Dihydrochloride Anhydrous,Pramipexole Hydrochloride Monohydrate,SND-919,Sifrol,2 Amino 6 propylaminotetrahydrobenzothiazole,SND 919
D013844	Thiazoles	Heterocyclic compounds where the ring system is composed of three CARBON atoms, a SULFUR and NITROGEN atoms.	Thiazole
D052160	Benzothiazoles	Compounds with a benzene ring fused to a thiazole ring.
D018491	Dopamine Agonists	Drugs that bind to and activate dopamine receptors.	Dopamine Receptor Agonists,Dopaminergic Agonists,Agonists, Dopamine Receptor,Agonists, Dopaminergic,Dopamine Agonist,Dopamine Receptor Agonist,Dopaminergic Agonist,Receptor Agonists, Dopamine,Agonist, Dopamine,Agonist, Dopamine Receptor,Agonist, Dopaminergic,Agonists, Dopamine,Receptor Agonist, Dopamine