Biomaterial Database

Determination of sorbitol and mannitol in pharmaceuticals by GLC of tris-n-butyldiboronate esters. 1975

D L Sondack

A rapid method for determining sorbitol or mannitol in pharmaceuticals by GLC using the tris-n-butyldiboronate esters is described. An internal standard unrelated to the hexitols is utilized to avoid the problems of cross-contamination introduced by the use of other hexitols.

UI	MeSH Term	Description	Entries
D008353	Mannitol	A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.	(L)-Mannitol,Osmitrol,Osmofundin
D001888	Boric Acids	Inorganic and organic derivatives of boric acid either B(OH)3 or, preferably H3BO3.	Acids, Boric
D001896	Boron Compounds	Inorganic or organic compounds that contain boron as an integral part of the molecule.	Borides,Compounds, Boron
D002849	Chromatography, Gas	Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.	Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D013012	Sorbitol	A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. It is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications.	Glucitol,Medevac,Sorbilax,Yal,klysma Sorbit