Relative pathogenicity of Candida tropicalis in rat tongue mucosa. 2000

E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
Department of Physiology, Faculty of Medicine, Safárik University, 040 66 Kosice, Slovakia.

The potential of C. tropicalis to colonize and infect rat tongue mucosa was demonstrated. Thirty female Sprague-Dawley rats were infected orally with three different strains of C. tropicalis. The animals were killed one and three weeks following the inoculation and sections of their tongue were stained with hematoxylin-eosin and Grocott stain. Histological changes were observed in the group of animals killed one week after inoculation and infected with C. tropicalis strain isolated from the crural ulcer of a diabetic patient. The most important finding was acute purulent myositis with the formation of abscesses. The myositis was local without signs of spreading to the surrounding tissue. Epithelium-penetrating hyphae observed in the Grocott-stained sections were relatively fewer and more sparsely distributed.

UI MeSH Term Description Entries
D009092 Mucous Membrane An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa. Lamina Propria,Mucosa,Mucosal Tissue,Muscularis Mucosae,Mucous Membranes,Membrane, Mucous,Membranes, Mucous,Mucosae, Muscularis,Mucosal Tissues,Propria, Lamina,Tissue, Mucosal,Tissues, Mucosal
D009220 Myositis Inflammation of a muscle or muscle tissue. Inflammatory Myopathy,Myositis, Focal,Myositis, Infectious,Idiopathic Inflammatory Myopathies,Idiopathic Inflammatory Myopathy,Idiopathic Inflammatory Myositis,Infectious Myositis,Inflammatory Muscle Diseases,Inflammatory Myopathies, Idiopathic,Inflammatory Myopathy, Idiopathic,Muscle Diseases, Inflammatory,Myopathies, Idiopathic Inflammatory,Myopathy, Inflammatory,Myositis, Proliferative,Focal Myositides,Focal Myositis,Infectious Myositides,Inflammatory Muscle Disease,Inflammatory Myopathies,Muscle Disease, Inflammatory,Myopathies, Inflammatory,Myopathy, Idiopathic Inflammatory,Myositides,Myositides, Focal,Myositides, Infectious,Myositides, Proliferative,Proliferative Myositides,Proliferative Myositis
D002175 Candida A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; VULVOVAGINAL CANDIDIASIS; and CANDIDIASIS, ORAL (THRUSH). Candida guilliermondii var. nitratophila,Candida utilis,Cyberlindnera jadinii,Hansenula jadinii,Lindnera jadinii,Monilia,Pichia jadinii,Saccharomyces jadinii,Torula utilis,Torulopsis utilis,Monilias
D002180 Candidiasis, Oral Infection of the mucous membranes of the mouth by a fungus of the genus CANDIDA. (Dorland, 27th ed) Moniliasis, Oral,Thrush,Candidiases, Oral,Moniliases, Oral,Oral Candidiases,Oral Candidiasis,Oral Moniliases,Oral Moniliasis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000038 Abscess Accumulation of purulent material in tissues, organs, or circumscribed spaces, usually associated with signs of infection. Abscesses
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014059 Tongue A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech. Tongues
D014060 Tongue Diseases Diseases involving the TONGUE. Microglossia,Disease, Tongue,Diseases, Tongue,Microglossias,Tongue Disease

Related Publications

E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
December 1960, Canadian Medical Association journal,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
July 1962, The Journal of pathology and bacteriology,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
December 1998, Journal of medical microbiology,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
August 2008, Biological & pharmaceutical bulletin,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
February 1977, Bollettino della Societa italiana di biologia sperimentale,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
August 1980, Infection and immunity,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
February 1964, Archiv fur Kinderheilkunde,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
March 2012, FEMS microbiology reviews,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
August 2010, Journal of medical microbiology,
E Dorko, and E Pilipcinec, and I Bracoková, and A Jenca, and E Svický, and J Danko, and L Tkáciková, and F Dorko, and M Kocisová, and K Lovásová
August 1976, Journal of medical microbiology,
Copied contents to your clipboard!