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Mineralogical analysis of bronchoalveolar lavage fluid (BALF) by electron microscopy can represent the most suitable method for assessing asbestos exposure. However, it has been claimed that no standardized or systematic approach to the subject of mineralogical analysis exists. This study aimed to evaluate BALF mineralogical analysis by transmission electron microscopy as biomarker of asbestos fiber load. BALF was examined in 108 exposed workers and 57 patients who underwent diagnostic fiberoptic bronchoscopy for various clinical purposes. Asbestos bodies in BALF were counted with a phase-contrast microscope. Fibers were counted and analyzed by transmission electron microscopy, which showed a significant difference between the two populations and positive results for all exposed subjects. Only 82.2% of the exposed population tested positive for asbestos bodies. Subjects with long-term exposure had higher concentrations of fibers than did those with more recent exposure, probably because of the higher workplace exposure levels in the past. The results of the study confirm that fiber concentration in BALF can be considered as a reliable biomarker of past asbestos exposure, even many years after the end of exposure.
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
December 1998,
American journal of respiratory and critical care medicine,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
September 1994,
American journal of industrial medicine,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
January 1988,
Zeitschrift fur Erkrankungen der Atmungsorgane,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
January 1995,
Archives of environmental health,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
December 1991,
Zentralblatt fur Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
March 1999,
Archivos de bronconeumologia,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
March 1987,
European journal of respiratory diseases,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
January 1987,
Revue des maladies respiratoires,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
April 2012,
Revue des maladies respiratoires,
P Sartorelli, and
G Scancarello, and
R Romeo, and
G Marcianò, and
P Rottoli, and
G Arcangeli, and
S Palmi
January 1997,
La Medicina del lavoro,
