Biomaterial Database

[Anti-Sm antibodies--marker antibodies in systemic lupus erythematosus (SLE)]. 2002

F Hiepe, and G Riemekasten, and A von Mikecz

Universitätsklinikum Charité Med. Klinik mit Schwerpunkt Rheumatologie und Klin. Immunologie Schumannstr. 20/21, 10117 Berlin, Germany.

UI	MeSH Term	Description	Entries
D008180	Lupus Erythematosus, Systemic	A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.	Libman-Sacks Disease,Lupus Erythematosus Disseminatus,Systemic Lupus Erythematosus,Disease, Libman-Sacks,Libman Sacks Disease
D002460	Cell Line	Established cell cultures that have the potential to propagate indefinitely.	Cell Lines,Line, Cell,Lines, Cell
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001323	Autoantibodies	Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.	Autoantibody
D001324	Autoantigens	Endogenous tissue constituents with the ability to interact with AUTOANTIBODIES and cause an immune response.	Autoantigen,Autologous Antigen,Autologous Antigens,Self-Antigen,Self-Antigens,Antigen, Autologous,Antigens, Autologous,Self Antigen,Self Antigens
D012680	Sensitivity and Specificity	Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	Specificity,Sensitivity,Specificity and Sensitivity
D015151	Immunoblotting	Immunologic method used for detecting or quantifying immunoreactive substances. The substance is identified by first immobilizing it by blotting onto a membrane and then tagging it with labeled antibodies.	Dot Immunoblotting,Electroimmunoblotting,Immunoelectroblotting,Reverse Immunoblotting,Immunoblotting, Dot,Immunoblotting, Reverse,Dot Immunoblottings,Electroimmunoblottings,Immunoblottings,Immunoblottings, Dot,Immunoblottings, Reverse,Immunoelectroblottings,Reverse Immunoblottings
D015415	Biomarkers	Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, ENVIRONMENTAL EXPOSURE and its effects, disease diagnosis; METABOLIC PROCESSES; SUBSTANCE ABUSE; PREGNANCY; cell line development; EPIDEMIOLOGIC STUDIES; etc.	Biochemical Markers,Biological Markers,Biomarker,Clinical Markers,Immunologic Markers,Laboratory Markers,Markers, Biochemical,Markers, Biological,Markers, Clinical,Markers, Immunologic,Markers, Laboratory,Markers, Serum,Markers, Surrogate,Markers, Viral,Serum Markers,Surrogate Markers,Viral Markers,Biochemical Marker,Biologic Marker,Biologic Markers,Clinical Marker,Immune Marker,Immune Markers,Immunologic Marker,Laboratory Marker,Marker, Biochemical,Marker, Biological,Marker, Clinical,Marker, Immunologic,Marker, Laboratory,Marker, Serum,Marker, Surrogate,Serum Marker,Surrogate End Point,Surrogate End Points,Surrogate Endpoint,Surrogate Endpoints,Surrogate Marker,Viral Marker,Biological Marker,End Point, Surrogate,End Points, Surrogate,Endpoint, Surrogate,Endpoints, Surrogate,Marker, Biologic,Marker, Immune,Marker, Viral,Markers, Biologic,Markers, Immune
D017411	Ribonucleoproteins, Small Nuclear	Highly conserved nuclear RNA-protein complexes that function in RNA processing in the nucleus, including pre-mRNA splicing and pre-mRNA 3'-end processing in the nucleoplasm, and pre-rRNA processing in the nucleolus (see RIBONUCLEOPROTEINS, SMALL NUCLEOLAR).	Small Nuclear Ribonucleoproteins,snRNP,Small Nuclear RNP,Small Nuclear Ribonucleoprotein,Small Nuclear Ribonucleoprotein Particle,Nuclear RNP, Small,Nuclear Ribonucleoprotein, Small,Nuclear Ribonucleoproteins, Small,RNP, Small Nuclear,Ribonucleoprotein, Small Nuclear
D055517	snRNP Core Proteins	The protein components that constitute the common core of small nuclear ribonucleoprotein particles. These proteins are commonly referred as Sm nuclear antigens due to their antigenic nature.	Sm Nuclear Antigens,SNRPN,SNRPN Protein,Sm Core Proteins,SmD Antigen,SmD Autoantigen,Small Nuclear Ribonucleoprotein B,Small Nuclear Ribonucleoprotein Core Proteins,Small Nuclear Ribonucleoprotein D1 Polypeptide 16kDa,Small Nuclear Ribonucleoprotein D2 Polypeptide 16.5kDa,Small Nuclear Ribonucleoprotein D3 Polypeptide 18kDa,Small Nuclear Ribonucleoprotein Polypeptide B',Small Nuclear Ribonucleoprotein Polypeptide B'',Small Nuclear Ribonucleoprotein Polypeptide B2,Small Nuclear Ribonucleoprotein Polypeptide E,Small Nuclear Ribonucleoprotein Polypeptide F,Small Nuclear Ribonucleoprotein Sm D1,Small Nuclear Ribonucleoprotein Sm D2,Small Nuclear Ribonucleoprotein-Associated Protein B,Small Nuclear Ribonucleoprotein-Associated Protein B1,Small Nuclear Ribonucleoprotein-Associated Protein B2,Small Nuclear Ribonucleoprotein-Associated Protein D1,Small Nuclear Ribonucleoprotein-Associated Protein D2,Small Nuclear Ribonucleoprotein-Associated Protein D3,Small Nuclear Ribonucleoprotein-Associated Protein E,Small Nuclear Ribonucleoprotein-Associated Protein F,Small Nuclear Ribonucleoprotein-Associated Protein N,snRNP Core Protein D1,Antigen, SmD,Antigens, Sm Nuclear,Autoantigen, SmD,Core Proteins, Sm,Core Proteins, snRNP,Nuclear Antigens, Sm,Small Nuclear Ribonucleoprotein Associated Protein B,Small Nuclear Ribonucleoprotein Associated Protein B1,Small Nuclear Ribonucleoprotein Associated Protein B2,Small Nuclear Ribonucleoprotein Associated Protein D1,Small Nuclear Ribonucleoprotein Associated Protein D2,Small Nuclear Ribonucleoprotein Associated Protein D3,Small Nuclear Ribonucleoprotein Associated Protein E,Small Nuclear Ribonucleoprotein Associated Protein F,Small Nuclear Ribonucleoprotein Associated Protein N