Biomaterial Database

[Safety threshold of fluorine in endemic fluorosis regions in China]. 2002

Yonghua Li, and Wuyi Wang, and Shaofan Hou

Institute of Geographic Sciences and Natural Resources Research, CAS, Beijing 100101, China.

Four endemic fluorosis regions in China and their environmental epidemiological characteristics were summarized in this paper. It shows that the epidemiology of endemic fluorosis is closely related to geochemical parameters of local environment. The food-web and dose-effect relationship of fluoride from environment to human body in different types of endemic fluorosis regions were studied. And the safety threshold of fluoride in different regions was determined. The results have provided a scientific basis for environmental risk assessment of fluoride in China.

UI	MeSH Term	Description	Entries
D009050	Fluorosis, Dental	A chronic endemic form of ENAMEL HYPOMINERALIZATION caused by drinking water with a high fluorine content during the time of tooth formation, and characterized by defective calcification that gives a white chalky appearance to the enamel, which gradually undergoes brown discoloration. (Jablonski's Dictionary of Dentistry, 1992, p286)	Dental Fluorosis,Mottled Enamel,Mottled Teeth,Dental Fluoroses,Fluoroses, Dental,Enamel, Mottled,Mottled Enamels,Teeth, Mottled
D002681	China	A country spanning from central Asia to the Pacific Ocean.	Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D003031	Coal	A natural fuel formed by partial decomposition of vegetable matter under certain environmental conditions.	Anthracite,Bituminous Coal,Brown Coal,Lignite,Lignitious Coal,Peat Coal,Soft Coal,Anthracites,Bituminous Coals,Brown Coals,Coal, Bituminous,Coal, Brown,Coal, Lignitious,Coal, Peat,Coal, Soft,Coals,Coals, Bituminous,Coals, Brown,Coals, Lignitious,Coals, Peat,Coals, Soft,Lignites,Lignitious Coals,Peat Coals,Soft Coals
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004785	Environmental Pollutants	Substances or energies, for example heat or light, which when introduced into the air, water, or land threaten life or health of individuals or ECOSYSTEMS.	Environmental Pollutant,Pollutant,Pollutants,Pollutants, Environmental,Pollutant, Environmental
D005461	Fluorine	A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.	Fluorine-19,Fluorine 19
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014881	Water Supply	Means or process of supplying water (as for a community) usually including reservoirs, tunnels, and pipelines and often the watershed from which the water is ultimately drawn. (Webster, 3d ed)	Supplies, Water,Supply, Water,Water Supplies
D018570	Risk Assessment	The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)	Assessment, Risk,Benefit-Risk Assessment,Risk Analysis,Risk-Benefit Assessment,Health Risk Assessment,Risks and Benefits,Analysis, Risk,Assessment, Benefit-Risk,Assessment, Health Risk,Assessment, Risk-Benefit,Benefit Risk Assessment,Benefit-Risk Assessments,Benefits and Risks,Health Risk Assessments,Risk Analyses,Risk Assessment, Health,Risk Assessments,Risk Benefit Assessment,Risk-Benefit Assessments