Biomaterial Database

[Study on hydrolysis conditions of Dioscorea nipponica with uniform design method]. 2002

Jun Wang, and Kedi Yang, and Jun Chen

Jiangsu University, Zhenjiang 212013.

OBJECTIVE To optimize hydrolysis conditions of Dioscorea nipponica so as to provide parameters for extracting diosgenin in industry. METHODS The optimum hydrolysis conditions were investigated using diosgenin as an index with uniform design and high performance liquid chromatography method. RESULTS The optimum conditions were as follows: the hydrochloric acid concentration was 2.5 mol/L, solid-liquid rate was 1:5, the reaction temperature was 140 degrees C, the reaction time was 4.0 h, the mix round speed was 120 r/min. CONCLUSIONS The content of diosgenin under the optimum hydrolysis conditions is raised, and the hydrochloric acid concentration should be strictly controlled because of its large influences on the results.

UI	MeSH Term	Description	Entries
D004144	Diosgenin	A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.
D004365	Drugs, Chinese Herbal	Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.	Chinese Herbal Drugs,Plant Extracts, Chinese,Chinese Drugs, Plant,Chinese Plant Extracts,Extracts, Chinese Plant,Herbal Drugs, Chinese
D006851	Hydrochloric Acid	A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.	Hydrogen Chloride,Muriatic Acid,Acid, Hydrochloric,Acid, Muriatic,Chloride, Hydrogen
D006868	Hydrolysis	The process of cleaving a chemical compound by the addition of a molecule of water.
D013678	Technology, Pharmaceutical	The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.	Technology, Pharmacy,Pharmaceutic Technology,Pharmaceutical Technology,Pharmacy Technology,Technology, Pharmaceutic
D013696	Temperature	The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.	Temperatures
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D027742	Dioscorea	A plant genus best known for edible underground tubers. Yam may also refer to a moist variety of sweet potato, IPOMOEA BATATAS.	Yam,Chinese Yam,Dioscorea batatas,Dioscorea opposita,Dioscorea polystachya,Dioscorea villosa,Shan Yao,Wild Yam,Chinese Yams,Shan Yaos,Wild Yams,Yam, Chinese,Yam, Wild,Yams,Yams, Chinese,Yams, Wild,Yao, Shan,Yaos, Shan