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A test of placental function was assessed by measurement of plasma oestradiol levels in 32 patients after intravenous injection of 50 mg dehydroepiandrosterone sulphate (DHAS). Every pregnant patient showed a rise in plasma oestradiol after DHAS; two puerperal patients showed no rise. It was not possible to distinguish the variable response in normal pregnancy from that in patients with severe hypertension and proteinuria or with retarded intrauterine fetal growth. The test was of no value in one hypertensive patient as a predictor of fetal death eight days later or, in another, to confirm fetal death of two days duration. Our results do not suggest that this test is a useful addition to currently available tests of placental endocrine function.
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
January 1981,
Acta obstetricia et gynecologica Scandinavica,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
October 1978,
Acta endocrinologica,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
January 1972,
Acta endocrinologica. Supplementum,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
June 1976,
British journal of obstetrics and gynaecology,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
November 1975,
Clinica chimica acta; international journal of clinical chemistry,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
February 1976,
Obstetrics and gynecology,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
October 1984,
Experimental and clinical endocrinology,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
February 1992,
Journal of endocrinological investigation,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
May 1988,
American journal of reproductive immunology and microbiology : AJRIM,
A R Korda, and
J J Challis, and
A B Anderson, and
A C Turnbull
March 1979,
Acta Europaea fertilitatis,
