Biomaterial Database

Disappearance of ethanol from isolated sheep rumen. 2003

T Veresegyházy, and Hedvig Fébel, and G Nagy, and Agnes Rimanóczy

Department of Physiology and Biochemistry, Faculty of Veterinary Science, Szent István University, H-1400 Budapest, P.O. Box 2, Hungary. tveres@univet.hu

The absorption of ethanol from the rumen was studied in three British Milk sheep equipped with a rumen cannula. After removal of the rumen content and washing the forestomachs several times the reticulo-omasal orifice was closed and through the cannula 20 or 60 ml ethanol and 2 ml Cr-EDTA were infused in physiological saline. The entire fluid volume was 3000 ml. At the start of the experiment (0 min) and subsequently in the 5th, 15th, 30th, 45th, 60th and 75th minutes samples were taken from the fluid present in the forestomachs. During the 75-min experiment the amount of ethanol gradually decreased in the rumen. The rate of disappearance varied according to concentration. The graph depicting the change of ruminal ethanol concentration shows a curve typical of passive transport. The equation describing the disappearance of ethanol was y = -0.0474x2 + 5.6544x + 10.869 after the administration of 20 ml ethanol, and y = -0.1377x2 + 19.541x - 24.606 after the infusion of 60 ml ethanol. It was established that ethanol was absorbed through the rumen wall by a passive transport process.

UI	MeSH Term	Description	Entries
D005260	Female		Females
D005285	Fermentation	Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.	Fermentations
D000042	Absorption	The physical or physiological processes by which substances, tissue, cells, etc. take up or take in other substances or energy.
D000431	Ethanol	A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.	Alcohol, Ethyl,Absolute Alcohol,Grain Alcohol,Alcohol, Absolute,Alcohol, Grain,Ethyl Alcohol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012417	Rumen	The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed)	Rumens
D034561	Sheep, Domestic	A species of sheep, Ovis aries, descended from Near Eastern wild forms, especially mouflon.	Mouflon,Ovis ammon aries,Ovis aries,Ovis aries musimon,Ovis gmelini musimon,Domestic Sheep,Mouflons