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9-deaza-5'-noraristeromycin. 2003

Meral Tuncbilek, and Stewart W Schneller
Department of Chemistry, Auburn University, Auburn, AL 36849, USA.

9-deaza-5'-noraristeromycin (2) has been prepared in 10 steps from the readily available (+)-(1R,4S)-4-t-butyldimethylsilyloxycyclopent-2-en-1-yl acetate. Compound 2 was evaluated against a large number of viruses. No activity was found nor did 2 display cyctotoxicity towards the viral host cells.

UI MeSH Term Description Entries
D000241 Adenosine A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. Adenocard,Adenoscan

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