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Previous investigations showed that quantitative immunofluorescence using antigens covalently bound to agarose particles represents a reproducible and sensitive assay for antibodies in experimental antisera. In this paper data are presented which show that also thyroglobulin antibodies in patients sera can be demonstrated using the defined antigen substrate spheres (DASS) system with thyroglobulin as antigen. Sera of 45 patients with various thyroid diseases were investigated for the presence of thyroglobulin antibodies using passive haemagglutination and the quantitative immunofluorescence technique. Comparable results were obtained with both techniques. Advantages and disadvantages of both methods are discussed.
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
November 1974,
Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
June 1975,
Annals of the New York Academy of Sciences,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
January 1976,
Journal of immunological methods,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
June 1975,
Annals of the New York Academy of Sciences,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
January 1975,
Annales de la Societe belge de medecine tropicale,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
March 1974,
Journal of immunological methods,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
April 1975,
Experimental parasitology,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
June 1975,
Experimental parasitology,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
November 1978,
Experimental parasitology,
W Knapp, and
H Ludwig, and
G Schernthaner, and
R Höfer, and
C Steffen
August 1974,
Journal of immunological methods,
