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Demonstration of HTLV-related proviral DNA sequences and antibodies reactive with HTLV internal proteins in an Hungarian patient with Sézary syndrome. 1992
Institute of Microbiology, University Medical School, Debrecen, Hungary.
DNA sequences distantly related to the proviral DNA of HTLV-I were found in the leukemic cells of a Hungarian patient suffering from Sézary syndrome. Serum samples from the patient contained antibodies reactive with the internal core polypeptides of HTLV-I and HTLV-II, but not with the env gene encoded type-specific HTLV antigens. The husband and daughter of the patient also had antibodies of the same specificity. These findings suggest the presence of a virus distantly related to HTLV-I and HTLV-II.
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