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To clarify the intracellular killing mechanisms of alveolar macrophages against Mycobacterium avium complex, effects of cytokines on O2- and NO2- production from normal and BCG-induced alveolar macrophages were studied. Intracellular growth of M. avium complex was inhibited in the alveolar macrophages stimulated by TNF, but not IFN. Enhancement of O2- production by normal alveolar macrophages stimulated by cytokines, was associated with the inhibition of intracellular growth of M. avium complex. However, when NO2- production by the alveolar macrophages was enhanced by the stimulating of IFN or IFN+TNF, in the presence L-arginine in the culture medium, their defense activity against M. avium complex decreased.
M Suga, and
T Doi, and
T Akaike, and
M Ando
January 1987,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
M Suga, and
T Doi, and
T Akaike, and
M Ando
July 1997,
Arzneimittel-Forschung,
M Suga, and
T Doi, and
T Akaike, and
M Ando
October 1989,
Microbial pathogenesis,
M Suga, and
T Doi, and
T Akaike, and
M Ando
September 1987,
The Journal of infectious diseases,
M Suga, and
T Doi, and
T Akaike, and
M Ando
January 2002,
BMC microbiology,
M Suga, and
T Doi, and
T Akaike, and
M Ando
June 1992,
The Journal of laboratory and clinical medicine,
M Suga, and
T Doi, and
T Akaike, and
M Ando
November 2022,
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy,
M Suga, and
T Doi, and
T Akaike, and
M Ando
May 1992,
Pathologie-biologie,
M Suga, and
T Doi, and
T Akaike, and
M Ando
February 1990,
Research in microbiology,
M Suga, and
T Doi, and
T Akaike, and
M Ando
September 1994,
Journal of immunology (Baltimore, Md. : 1950),
