[The use of an adrenal 11-beta-hydroxylase inhibitor (Metopirone) in the diagnosis of nanism]. 1961

L PICENI-SERENI, and L DE RITIS, and F SERENI

UI MeSH Term Description Entries
D008797 Metyrapone An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME. Methbipyranone,Methopyrapone,Metopiron,Metopirone,Métopirone,SU 4885
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D004392 Dwarfism A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is significantly below the average height. Nanism
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000305 Adrenal Cortex Hormones HORMONES produced by the ADRENAL CORTEX, including both steroid and peptide hormones. The major hormones produced are HYDROCORTISONE and ALDOSTERONE. Adrenal Cortex Hormone,Corticoid,Corticoids,Corticosteroid,Corticosteroids,Cortex Hormone, Adrenal,Hormone, Adrenal Cortex,Hormones, Adrenal Cortex
D013252 Steroid 11-beta-Hydroxylase A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). CYP11B1,Cytochrome P-450 CYP11B1,Cytochrome P-450(11 beta),Steroid 11-beta-Monooxygenase,11 beta-Hydroxylase,CYP 11B1,Cytochrome P450 11B1,Steroid 11 Hydroxylase,Steroid 11-Hydroxylase,Steroid-11-Hydroxylase,11 beta Hydroxylase,Cytochrome P 450 CYP11B1,Steroid 11 beta Hydroxylase,Steroid 11 beta Monooxygenase

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