Biomaterial Database

Histology of the capsules causing constrictive fibrosis around breast implants. 1977

J Smahel

Histological features seen in 9 capsules formed around breast prostheses with Dacron patches were described. Dacron evoked a marked foreign body reaction and fibroplasia. Parts of the silicone layer in which the Dacron fibres were originally anchored may also get into the capsule together with the Dacron. The main cause of fibrotic thickening in the capsules was contamination of the tissues with a foreign material, very probably silicone. The contamination of the capsules showed individual and local variation, with no definite correlation to the time which has elapsed since implantation.

UI	MeSH Term	Description	Entries
D011093	Polyethylene Terephthalates	Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.	Dacron,Nalophan,PET Polymer,Poly(Ethylene Terephtalate),Polyethylene Terephthalate,Tedlar,Dacrons,Nalophans,PET Polymers,Tedlars,Terephthalate, Polyethylene,Terephthalates, Polyethylene
D001940	Breast	In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.	Breasts
D005260	Female		Females
D005549	Foreign-Body Reaction	Chronic inflammation and granuloma formation around irritating foreign bodies.	Foreign Body Reaction,Reaction, Foreign-Body
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012828	Silicones	A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)	Silicone
D013518	Surgery, Plastic	The branch of surgery concerned with restoration, reconstruction, or improvement of defective, damaged, or missing structures.	Cosmetic Surgery,Esthetic Surgery,Plastic Surgery,Surgery, Cosmetic,Surgery, Esthetic,Reconstructive Surgery,Surgery, Reconstructive
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D019736	Prostheses and Implants	Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.	Implants, Artificial,Prostheses and Implant,Prosthesis,Prosthetic Implant,Endoprostheses,Endoprosthesis,Prostheses,Prosthetic Implants,Artificial Implant,Artificial Implants,Implant and Prostheses,Implant, Artificial,Implant, Prosthetic,Implants and Prostheses,Implants, Prosthetic