Bicyclic nucleoside inhibitors of varicella-zoster virus: synthesis and biological evaluation of 2',3'-dideoxy-3'-fluoro and 2'-deoxy-xylo derivatives. 2003

A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
Welsh School of Pharmacy, University of Wales Cardiff, Cardiff, UK.

UI MeSH Term Description Entries
D007202 Indicators and Reagents Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499) Indicator,Reagent,Reagents,Indicators,Reagents and Indicators
D008958 Models, Molecular Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures. Molecular Models,Model, Molecular,Molecular Model
D009705 Nucleosides Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed) Nucleoside,Nucleoside Analog,Nucleoside Analogs,Analog, Nucleoside,Analogs, Nucleoside
D005459 Fluorides Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices. Fluoride
D000212 Acyclovir A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes. Acycloguanosine,9-((2-Hydroxyethoxy)methyl)guanine,Aci-Sanorania,Acic,Aciclobeta,Aciclostad,Aciclovir,Aciclovir Alonga,Aciclovir-Sanorania,Acifur,Acipen Solutab,Acivir,Activir,Acyclo-V,Acyclovir Sodium,Antiherpes Creme,Avirax,Cicloferon,Clonorax,Cusiviral,Genvir,Herpetad,Herpofug,Herpotern,Herpoviric,Isavir,Laciken,Mapox,Maynar,Milavir,Opthavir,Supraviran,Viclovir,Vipral,Virax-Puren,Virherpes,Virmen,Virolex,Virupos,Virzin,Wellcome-248U,Zoliparin,Zovirax,Zyclir,aciclovir von ct,Aci Sanorania,Aciclovir Sanorania,Acyclo V,Alonga, Aciclovir,Sodium, Acyclovir,Solutab, Acipen,Virax Puren,ViraxPuren,Wellcome 248U,Wellcome248U
D000998 Antiviral Agents Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. Antiviral,Antiviral Agent,Antiviral Drug,Antivirals,Antiviral Drugs,Agent, Antiviral,Agents, Antiviral,Drug, Antiviral,Drugs, Antiviral
D001643 Bridged Bicyclo Compounds Saturated alicyclic hydrocarbon molecules consisting of two rings that have two non-adjacent atoms in common. Bicyclo Compounds,Bicyclo Compounds, Bridged
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D014645 Herpesvirus 3, Human The type species of VARICELLOVIRUS causing CHICKENPOX (varicella) and HERPES ZOSTER (shingles) in humans. Chickenpox Virus,Herpes zoster Virus,Ocular Herpes zoster Virus,VZ Virus,Varicella-Zoster Virus,HHV-3,Herpesvirus 3 (alpha), Human,Herpesvirus Varicellae,Human Herpesvirus 3,Chickenpox Viruses,Herpes zoster Viruses,VZ Viruses,Varicella Zoster Virus,Varicella-Zoster Viruses,Varicellae, Herpesvirus
D014994 Xylose D-Xylose,D Xylose

Related Publications

A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
January 2003, Nucleosides, nucleotides & nucleic acids,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
November 2004, Antiviral chemistry & chemotherapy,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
October 2010, Antiviral chemistry & chemotherapy,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
November 2000, Antiviral chemistry & chemotherapy,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
December 2007, The Journal of antimicrobial chemotherapy,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
June 2019, Molecules (Basel, Switzerland),
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
August 2013, Carbohydrate research,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
July 2002, The Journal of antimicrobial chemotherapy,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
January 2001, Nucleosides, nucleotides & nucleic acids,
A Carangio, and C McGuigan, and G Andrei, and R Snoeck, and E De Clercq, and J Balzarini
January 2018, European journal of medicinal chemistry,
Copied contents to your clipboard!