Biomaterial Database

Reduction of aflatoxin M1 in milk using hydrogen peroxide and hydrogen peroxide plus heat treatment. 1992

I Aman

Faculty of Veterinary Medicine, Cairo University, Egypt.

Use of hydrogen peroxide (H2O2) under various conditions of temperature and time to inactivate aflatoxin M1 in artificially contaminated raw milk was examined. The degree of inactivation was measured by Enzym Linked Immunosorbent Assay (ELISA). It appeared that there is no change in the content of aflatoxin M1 in milk contained H2O2 and examined after 24 hours without heat treatment and in contaminated milk without add of H2O2 and heat treated treatment at (63 degrees C for 30 min, 75 degrees C for 15 sec) but slight inactivation (4.3%) was obtained in milk boiled for 5 min without H2O2. Maximum inactivation (27.8%, 28.8% and 45.1%) were obtained using 1% H2O2 followed by heat treatment at 36 degrees C for 30 min, 75 degrees C for 15 sec and boiling for 5 min respectively.

UI	MeSH Term	Description	Entries
D008892	Milk	The off-white liquid secreted by the mammary glands of humans and other mammals. It contains proteins, sugar, lipids, vitamins, and minerals.	Cow Milk,Cow's Milk,Milk, Cow,Milk, Cow's
D005506	Food Contamination	The presence in food of harmful, unpalatable, or otherwise objectionable foreign substances, e.g. chemicals, microorganisms or diluents, before, during, or after processing or storage.	Food Adulteration,Adulteration, Food,Adulterations, Food,Contamination, Food,Contaminations, Food,Food Adulterations,Food Contaminations
D006358	Hot Temperature	Presence of warmth or heat or a temperature notably higher than an accustomed norm.	Heat,Hot Temperatures,Temperature, Hot,Temperatures, Hot
D006861	Hydrogen Peroxide	A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.	Hydrogen Peroxide (H2O2),Hydroperoxide,Oxydol,Perhydrol,Superoxol,Peroxide, Hydrogen
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D016607	Aflatoxin M1	A 4-hydroxylated metabolite of AFLATOXIN B1, one of the MYCOTOXINS from ASPERGILLUS tainted food. It is associated with LIVER damage and cancer resulting from its P450 activation to the epoxide which alkylates DNA. Toxicity depends on the balance of liver enzymes that activate it (CYTOCHROME P-450) and others that detoxify it (GLUTATHIONE S TRANSFERASE) (Pharmac Ther 50.443 1991). Primates & rat are sensitive while mouse and hamster are tolerant (Canc Res 29.236 1969).	Aflatoxin M(1),4-Hydroxyaflatoxin B1,Aflatoxin M,Aflatoxin M1, cis(+-)-Isomer,4 Hydroxyaflatoxin B1