Biomaterial Database

Cytotoxicity of corroded gallium and dental amalgam alloys. An in vitro study. 1992

V Psarras, and A Wennberg, and T Dérand

Department of Prosthetic Dentistry, Faculty of Odontology, Lund University, Malmö, Sweden.

The cytotoxicity of one gallium and three different dental amalgam alloys was assessed in a cell culture system. Two evaluation methods were used, the filter method and an extraction method. Before being tested, set specimens of the alloys were stored in 0.9% NaCl solution for 1 and 10 weeks, to corrode. The alloys showed various degrees of cytotoxicity, ranging from mild to marked. Differences were found between the two testing methods, but in most cases no major differences in cytotoxicity were found between the Ga alloy and the amalgams. The results encourage further study and development of the Ga alloy, which is mercury-free.

UI	MeSH Term	Description	Entries
D008851	Micropore Filters	A membrane or barrier with micrometer sized pores used for separation purification processes.	Millipore Filters,Filter, Micropore,Filter, Millipore,Filters, Micropore,Filters, Millipore,Micropore Filter,Millipore Filter
D002470	Cell Survival	The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.	Cell Viability,Cell Viabilities,Survival, Cell,Viabilities, Cell,Viability, Cell
D002478	Cells, Cultured	Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.	Cultured Cells,Cell, Cultured,Cultured Cell
D003343	Corrosion	The gradual destruction of a metal or alloy due to oxidation or action of a chemical agent. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Corrosions
D003470	Culture Media	Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.	Media, Culture
D003722	Dental Alloys	A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions for use in restorative or prosthetic dentistry.	Alloy, Dental,Alloys, Dental,Dental Alloy
D003723	Dental Amalgam	An alloy used in restorative dentistry that contains mercury, silver, tin, copper, and possibly zinc.	Amalgam, Dental,Amalgams, Dental,Dental Amalgams
D005708	Gallium	A rare, metallic element designated by the symbol, Ga, atomic number 31, and atomic weight 69.72.
D001672	Biocompatible Materials	Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.	Biomaterials,Bioartificial Materials,Hemocompatible Materials,Bioartificial Material,Biocompatible Material,Biomaterial,Hemocompatible Material,Material, Bioartificial,Material, Biocompatible,Material, Hemocompatible
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor