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Vitamin D or D-hormone stimulates calcium absorption in intestine, and suppresses PTH synthesis and secretion from parathyroid glands. On the other hand, recent basic and clinical studies implied the existence of the direct action of vitamin D on bone, which causes the stimulatory effects on bone formation. In addition, our recent study demonstrated that 1alpha (OH) D(3) at a dose commonly prescribed for osteoporosis stimulated bone formation transiently by measuring bone-specific biochemical markers in a clinical setting.
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