[Vitamin D analogs and calcium metabolism - bone-selective analogs -]. 2003

Toshio Okano
Department of Hygienic Sciences, Kobe Pharmaceutical University.

2MD [2-methylene-19-nor- (20S) -1alpha, 25 (OH)(2)D(3)] is a bone-selective vitamin D analog that has been developed on the basis of structure-function study. The bone-selective action of the analog has been tested and confirmed both in vitro and in vivo and its clinical application as a medication for bone diseases is anticipated although its adverse effects remain unclear.

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