[Changes in cardiac contractility induced by stimulation of hypothalamic ventromedial nucleus]. 1992

W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
Department of Physiology, Second Military Medical University, Shanghai.

Experiments were performed on anesthetized cats to observe the effect of electrical stimulation of the hypothalamic ventromedial nucleus (VMH) on cardiac contractility as judged by the change in LVSP, dp/dtmax, Vmax, P-dp/dt, P-lndp/dt. Electrical stimulation of VMH induced an augment response in cardiac force, while stimulation of an area between VMH and the third ventricle led only to a decrease in cardiac contractile force. All these changes were not accompanied by significant changes in heart rate and unaffected by bilateral vagotomy. The present experiment indicates that the inotropic and chronotropic regulation centers of cardiac function exist in different hypothalamic areas.

UI MeSH Term Description Entries
D008297 Male Males
D009200 Myocardial Contraction Contractile activity of the MYOCARDIUM. Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004558 Electric Stimulation Use of electric potential or currents to elicit biological responses. Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D005260 Female Females
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014697 Ventromedial Hypothalamic Nucleus A nucleus of the middle hypothalamus, the largest cell group of the tuberal region with small-to-medium size cells. Hypothalamic Nucleus, Ventromedial,Nucleus, Ventromedial Hypothalamic

Related Publications

W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
December 1963, The American journal of cardiology,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
August 1991, Brain research. Developmental brain research,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
March 1980, Experimental neurology,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
January 1983, Folia morphologica,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
March 1980, Indian journal of experimental biology,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
May 1973, Brain research,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
May 1971, Physiology & behavior,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
May 1982, Brain research,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
November 1983, Brain research,
W J Fu, and G X Hou, and J G Chen, and Z D Chen, and Y Cao, and Z D Lu
January 1975, Pharmacology, biochemistry, and behavior,
Copied contents to your clipboard!