Relation of changes in hepatitis B virus replication markers to the outcome of interferon treatment in patients with chronic hepatitis. 1992

S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
Istituto di Clinica Malattie Infettive, Prima Facoltà di Medicina, Università di Napoli, Italy.

The relationship between the behavior of hepatitis B virus (HBV) replication markers and the response to treatment with recombinant alpha-2b interferon (IFN) was investigated in 11 patients with chronic hepatitis. At the end of 6 months of treatment, 4 patients showed a complete response to IFN: 2 more patients had seroconversion to HBeAb after 8 and 9 months of follow-up, respectively. The response to IFN was partial in the remaining patients. Pre-treatment levels of HBV DNA in patients showing complete response were lower than pre-treatment levels in patients with partial response: in addition, serum HBV DNA clearance during the treatment was associated with sustained remission more frequently than changes in the HBeAg/HBeAb system.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011994 Recombinant Proteins Proteins prepared by recombinant DNA technology. Biosynthetic Protein,Biosynthetic Proteins,DNA Recombinant Proteins,Recombinant Protein,Proteins, Biosynthetic,Proteins, Recombinant DNA,DNA Proteins, Recombinant,Protein, Biosynthetic,Protein, Recombinant,Proteins, DNA Recombinant,Proteins, Recombinant,Recombinant DNA Proteins,Recombinant Proteins, DNA
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004279 DNA, Viral Deoxyribonucleic acid that makes up the genetic material of viruses. Viral DNA
D005260 Female Females
D006508 Hepatitis Antibodies Immunoglobulins raised by any form of viral hepatitis; some of these antibodies are used to diagnose the specific kind of hepatitis. Antibodies, Hepatitis
D006509 Hepatitis B INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. Hepatitis B Virus Infection
D006513 Hepatitis B e Antigens A closely related group of antigens found in the plasma only during the infective phase of hepatitis B or in virulent chronic hepatitis B, probably indicating active virus replication; there are three subtypes which may exist in a complex with immunoglobulins G. HBeAg,Hepatitis B e Antigen,Hepatitis Be Antigen,e Antigen,e Antigens,HBe Ag-1,HBe Ag-2,Hepatitis Be Antigens,Antigen, Hepatitis Be,Antigen, e,Antigens, Hepatitis Be,Antigens, e,Be Antigen, Hepatitis,Be Antigens, Hepatitis
D006515 Hepatitis B virus The type species of the genus ORTHOHEPADNAVIRUS which causes human HEPATITIS B and is also apparently a causal agent in human HEPATOCELLULAR CARCINOMA. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum. Dane Particle,Hepatitis Virus, Homologous Serum,B virus, Hepatitis,Hepatitis B viruses,Particle, Dane,viruses, Hepatitis B

Related Publications

S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
February 1988, American journal of clinical pathology,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
December 1989, Gastroenterologia Japonica,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
June 1981, The Journal of infectious diseases,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
May 1986, Revista clinica espanola,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
January 1983, Vox sanguinis,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
January 1991, Sovetskaia meditsina,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
June 2006, Nan fang yi ke da xue xue bao = Journal of Southern Medical University,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
February 1979, Journal of clinical & laboratory immunology,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
March 1979, Gut,
S Nardiello, and M Gargiulo, and T Pizzella, and L Digilio, and L Di Ottavio, and B Galanti
November 2006, World journal of gastroenterology,
Copied contents to your clipboard!