Biomaterial Database

Electro-oculography of smooth pursuit and optokinetic nystagmus eye movements in type I Duane's retraction syndrome. 2006

Nélida B Melek, and Susana Blanco, and Horacio Garcia

Instituto de Cálculo, Ciudad Universitaria-PII, 1428 Ciudad de Buenos Aires, Argentina.

BACKGROUND These two eye movements have not been previously studied in this condition by this method. METHODS Five cases were studied. Both visual acuity and eye examination of anterior and posterior segments were normal. A Nicolet Nystar Plus system with chloride silver electrodes was used to record the EOG. RESULTS Of the two systems under study, the smooth pursuit system showed the most relevant anomalies, both in the Duane's eye and in the apparently healthy eye. No correlation was found between the pursuit and optokinetic nystagmus disorders. In some cases, more significant abnormalities were observed in the clinically normal eye. CONCLUSIONS The results clearly demonstrated a significant impairment of the pursuit system. This suggests that this motor disorder is not exclusively caused by hypoplasia or aplasia of the nucleus of the abducens nerve (VIth cranial nerve). These abnormalities might be related to a poor development of the rhombencephalon since both supramotor nuclei as well as the pathways of this system arise from this region of the embryonic brain. In the particular case of OKN, the supramotor nuclei have a different origin. Therefore, these systems might be affected differently.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009801	Oculomotor Muscles	The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris.	Extraocular Muscles,Extraocular Rectus Muscles,Inferior Oblique Extraocular Muscle,Inferior Oblique Muscles,Levator Palpebrae Superioris,Musculus Orbitalis,Oblique Extraocular Muscles,Oblique Muscle, Inferior,Oblique Muscle, Superior,Oblique Muscles, Extraocular,Rectus Muscles, Extraocular,Superior Oblique Extraocular Muscle,Superior Oblique Muscle,Extraocular Muscle,Extraocular Muscle, Oblique,Extraocular Muscles, Oblique,Extraocular Oblique Muscle,Extraocular Oblique Muscles,Extraocular Rectus Muscle,Inferior Oblique Muscle,Muscle, Oculomotor,Muscles, Oculomotor,Oblique Extraocular Muscle,Oblique Muscle, Extraocular,Oblique Muscles, Inferior,Oblique Muscles, Superior,Oculomotor Muscle,Rectus Muscle, Extraocular,Superior Oblique Muscles
D009802	Oculomotor Nerve	The 3d cranial nerve. The oculomotor nerve sends motor fibers to the levator muscles of the eyelid and to the superior rectus, inferior rectus, and inferior oblique muscles of the eye. It also sends parasympathetic efferents (via the ciliary ganglion) to the muscles controlling pupillary constriction and accommodation. The motor fibers originate in the oculomotor nuclei of the midbrain.	Cranial Nerve III,Third Cranial Nerve,Nerve III,Nervus Oculomotorius,Cranial Nerve IIIs,Cranial Nerve, Third,Cranial Nerves, Third,Nerve IIIs,Nerve, Oculomotor,Nerve, Third Cranial,Nerves, Oculomotor,Nerves, Third Cranial,Oculomotor Nerves,Oculomotorius, Nervus,Third Cranial Nerves
D011698	Pursuit, Smooth	Eye movements that are slow, continuous, and conjugate and occur when a fixed object is moved slowly.	Pursuits, Smooth,Smooth Pursuit,Smooth Pursuits
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D004370	Duane Retraction Syndrome	A syndrome characterized by marked limitation of abduction of the eye, variable limitation of adduction and retraction of the globe, and narrowing of the palpebral fissure on attempted adduction. The condition is caused by aberrant innervation of the lateral rectus by fibers of the OCULOMOTOR NERVE.	Duane Syndrome,Ocular Retraction Syndrome,Acrorenoocular Syndrome,Co-Contractive Retraction Syndrome,Duane Anomaly,Duane Anomaly with Radial Abnormalities and Deafness,Duane Anomaly with Radial Ray Abnormalities and Deafness,Duane Anomaly, Isolated,Duane Retraction Syndrome 1,Duane Retraction Syndrome 2,Duane Retraction Syndrome, Type 1,Duane Retraction Syndrome, Type 2,Duane Retraction Syndrome, Type 3,Duane's Syndrome,Duane-Radial Ray Syndrome,Isolated Duane Retraction Syndrome,Okihiro Syndrome,Retraction Syndrome,Stilling-Turk-Duane Syndrome,Type 1 Duane Retraction Syndrome,Type 2 Duane Retraction Syndrome,Type 3 Duane Retraction Syndrome,Acrorenoocular Syndromes,Anomaly, Duane,Anomaly, Isolated Duane,Co Contractive Retraction Syndrome,Co-Contractive Retraction Syndromes,Duane Anomalies, Isolated,Duane Radial Ray Syndrome,Duanes Syndrome,Isolated Duane Anomalies,Isolated Duane Anomaly,Ocular Retraction Syndromes,Retraction Syndrome, Co-Contractive,Retraction Syndrome, Duane,Retraction Syndrome, Ocular,Retraction Syndromes,Stilling Turk Duane Syndrome,Stilling-Turk-Duane Syndromes,Syndrome, Acrorenoocular,Syndrome, Duane,Syndrome, Duane Retraction,Syndrome, Duane's,Syndrome, Duane-Radial Ray,Syndrome, Ocular Retraction,Syndrome, Okihiro
D004585	Electrooculography	Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.	EOG,Electrooculograms,Electrooculogram
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000010	Abducens Nerve	The 6th cranial nerve which originates in the ABDUCENS NUCLEUS of the PONS and sends motor fibers to the lateral rectus muscles of the EYE. Damage to the nerve or its nucleus disrupts horizontal eye movement control.	Cranial Nerve VI,Sixth Cranial Nerve,Abducent Nerve,Nerve VI,Nervus Abducens,Abducen, Nervus,Abducens, Nervus,Abducent Nerves,Cranial Nerve VIs,Cranial Nerve, Sixth,Nerve VI, Cranial,Nerve VIs,Nerve VIs, Cranial,Nerve, Abducens,Nerve, Abducent,Nerve, Sixth Cranial,Nerves, Sixth Cranial,Nervus Abducen,Sixth Cranial Nerves