[Antimicrobial susceptibility of Pseudomonas aeruginosa clinical isolates in Castellón, Spain]. 2006

B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
Servicio de Microbiología, Hospital General de Castellon, Castellón, Spain.

A retrospective study of the susceptibility to antimicrobials (amikacin, tobramycin, gentamicin, ceftazidime, cefepime, piperacillin, piperacil-lin-tazobactam, imipenem, meropenem and ciprofloxacin) of 5,811 Pseudomonas aeruginosa isolates was performed in a general hospital over a period of 12 years. The majority of isolates was from respiratory samples (31.99%), followed by urine samples (26.36%) and ear samples (10.51%). There was a predominance of hospital strains (69.66%); 50.30% of those from medical services, 31.74% from critical care services (mainly ICU) and the remaining from surgical services. No antimicrobial included in our study showed an activity over all isolated strains. In health centers the majority of antimicrobials showed good activity, with a percentage of resistance less than 10%. However, hospital strains showed that only amikacin, piperacillin-tazobactam and meropenem had a percentage of resistance near or lower than 10%. In both environments, gentamicin presented with the highest percentage of resistance. Strains from patients hospitalized in critical care services showed an elevated resistance to tobramycin, imipenem and ceftazidime, while strains from patients in medical services showed resistance to ciprofloxacin. Similar studies published in Spain confirm the importance of conducting local studies in order to understand the antimicrobial susceptibility of P. aeruginosa in each region, and especially to carry out empirically based treatments.

UI MeSH Term Description Entries
D010033 Otitis Media Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE. Middle Ear Inflammation,Inflammation, Middle Ear
D011550 Pseudomonas aeruginosa A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection. Bacillus aeruginosus,Bacillus pyocyaneus,Bacterium aeruginosum,Bacterium pyocyaneum,Micrococcus pyocyaneus,Pseudomonas polycolor,Pseudomonas pyocyanea
D011552 Pseudomonas Infections Infections with bacteria of the genus PSEUDOMONAS. Infections, Pseudomonas,Pseudomonas aeruginosa Infection,Infection, Pseudomonas,Pseudomonas Infection,Pseudomonas aeruginosa Infections
D012141 Respiratory Tract Infections Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases. Respiratory System Infections,Upper Respiratory Tract Infection,Upper Respiratory Tract Infections,Infections, Respiratory,Infections, Respiratory Tract,Infections, Upper Respiratory,Infections, Upper Respiratory Tract,Respiratory Infections,Upper Respiratory Infections,Infection, Respiratory System,Infection, Respiratory Tract,Respiratory Infection, Upper,Respiratory System Infection,Respiratory Tract Infection
D003428 Cross Infection Any infection which a patient contracts in a health-care institution. Hospital Infections,Nosocomial Infections,Health Care Associated Infection,Health Care Associated Infections,Healthcare Associated Infections,Infection, Cross,Infections, Hospital,Infections, Nosocomial,Cross Infections,Healthcare Associated Infection,Hospital Infection,Infection, Healthcare Associated,Infection, Hospital,Infection, Nosocomial,Infections, Cross,Infections, Healthcare Associated,Nosocomial Infection
D004351 Drug Resistance Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration. Resistance, Drug
D006748 Hospital Departments Major administrative divisions of the hospital. Departments, Hospital,Department, Hospital,Hospital Department
D006769 Hospitals, General Large hospitals with a resident medical staff which provides continuous care to maternity, surgical and medical patients. General Hospital,General Hospitals,Hospital, General
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

Related Publications

B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
December 2003, Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
March 2010, Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
March 1995, The Canadian veterinary journal = La revue veterinaire canadienne,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
June 2004, Saudi medical journal,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
May 1987, Gaoxiong yi xue ke xue za zhi = The Kaohsiung journal of medical sciences,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
July 2008, The Journal of urology,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
April 2009, The Malaysian journal of medical sciences : MJMS,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
July 2023, Pathogens (Basel, Switzerland),
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
January 2019, PeerJ,
B Gomila Sard, and F J Pardo Serrano, and R Moreno Muñoz, and E Celades Porcar, and A García del Busto Remón
February 2007, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi,
Copied contents to your clipboard!