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Concentrations of cyclic AMP were measured in rabbit ovaries at various times after injection of an ovulatory dose of human chorionic gonadotrophin (HCG). A biphasic increase in cyclic AMP concentration occurred during the preovulatory period, with peaks 30 min and 3-4 h after HCG injection. Concentrations of cyclic AMP had returned to those observed in ovaries of control oestrous animals before the onset of ovulation 10-12 h after administration of HCG, and remained low throughout the period of pseudopregnancy. Concentrations of cyclic AMP in the newly formed and developing corpora lutea were similar to the concentrations observed in the remainder of the tissue during this period. No significant increase in cyclic AMP concentration was observed 7-9 days after initiation of ovulation. Concentrations of ATP were also investigated during the preovulatory period. The dose-response relationship of HCG to cyclic AMP production in oestrous rabbit ovaries was investigated.
A K Goff, and
P W Major
June 1984,
Acta endocrinologica,
A K Goff, and
P W Major
December 1995,
Human reproduction (Oxford, England),
A K Goff, and
P W Major
November 1977,
Journal of reproduction and fertility,
A K Goff, and
P W Major
January 1973,
Hormone research,
A K Goff, and
P W Major
October 1980,
Acta endocrinologica,
A K Goff, and
P W Major
July 1967,
The Veterinary record,
A K Goff, and
P W Major
October 1995,
Human reproduction (Oxford, England),
A K Goff, and
P W Major
April 1984,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
A K Goff, and
P W Major
October 1977,
The Journal of endocrinology,
A K Goff, and
P W Major
February 1975,
Life sciences,
