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CT brain scans of 65 alcohol-dependent inpatients were compared before and after 6 weeks of confirmed abstinence. Linear measurements revealed a significant reduction of the enlargement of the ventricular system in accordance with the re-expansion of the brain after alcohol abstinence (ANOVA, significant time effects). 22 patients showed a moderate or severe thiamine deficiency. CT findings on thiamine-deficient patients did not differ from those on patients without thiamine deficiency (ANOVA, no significant group effects). Correlations between thiamine deficiency and subcortical atrophy before treatment were not significant. The results are discussed in relation to the pathogenesis of reversible brain shrinkage in chronic alcoholics.
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
January 2003,
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
January 1970,
The British journal of addiction to alcohol and other drugs,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
August 1984,
No to shinkei = Brain and nerve,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
March 1995,
Metabolic brain disease,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
February 1993,
Alcoholism, clinical and experimental research,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
January 1969,
Acta vitaminologica et enzymologica,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
November 1996,
Journal of studies on alcohol,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
April 1995,
Alcoholism, clinical and experimental research,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
January 1994,
British medical bulletin,
K Mann, and
G Schroth, and
F Stetter, and
H W Schied, and
M Bartels, and
A Batra, and
H Heimann
March 1985,
Journal of neurology, neurosurgery, and psychiatry,
