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In an experiment performed to investigate the effect of LH-RH on the anterior pituitary of rats, we studied the changes in the concentration of 3',5'-cyclic AMP in the anterior pituitary and the uridine uptake by the anterior pituitary following the intravenous injection of 100 ng LH-RH. The results obtained are summarized as follows: 1) The tissue level of 3',5'-cyclic AMP in the anterior pituitary reached the highest peak 15 min after the injection of LH-RH. 2) The uridine uptake of the anterior pituitary began to increase 15 min after the LH-RH injection and attained a maximum level (5 to 6 times the normal level) in 30 min. 3) The fact that the uridine uptake was inhibited to a considerable extent by the addition of actinomycin D to the incubation medium suggested that uridine was incorporated into the RNA fraction.
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
January 1973,
Metabolism: clinical and experimental,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
January 1975,
Molecular and cellular endocrinology,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
May 1982,
Nihon Sanka Fujinka Gakkai zasshi,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
March 1980,
Revista espanola de fisiologia,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
January 1981,
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T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
May 1977,
Molecular and cellular endocrinology,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
May 1972,
Acta endocrinologica,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
January 1976,
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T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
July 1977,
Nihon Naibunpi Gakkai zasshi,
T Yoshida, and
Y Hattori, and
H Hoshiai, and
M Hirano, and
K Takahashi
April 1978,
Molecular and cellular endocrinology,
