BIOMAT Database Logo BIOMAT Database Logo

Spindle cell carcinoma of the external auditory meatus with intracranial extension: histological, immunohistochemical and electron microscopic evaluation. 2007

Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
ENT Clinic G. Lugli, Department of Ophthalmology and Otolaryngology, Bari, Italy. otorino1@orl.uniba.it

We present a case of squamous spindle cell carcinoma of the external auditory meatus in a 38-year-old man. The tumour was extended to the inner ear, the temporal bone, the middle cranial fossa and the meningo-cerebral tissue. The surgical intervention of temporo-occipital craniotomy removed most of the neoplasia. At pathologic examination, the tumour showed an undifferentiated spindle cell pattern. Immunohistochemistry with a large antibody panel found a weak positivity only to EMA. The diagnosis was made when the electron microscopy showed rare junctional structures and tonofilaments.

UI MeSH Term Description Entries
D007150 Immunohistochemistry Histochemical localization of immunoreactive substances using labeled antibodies as reagents. Immunocytochemistry,Immunogold Techniques,Immunogold-Silver Techniques,Immunohistocytochemistry,Immunolabeling Techniques,Immunogold Technics,Immunogold-Silver Technics,Immunolabeling Technics,Immunogold Silver Technics,Immunogold Silver Techniques,Immunogold Technic,Immunogold Technique,Immunogold-Silver Technic,Immunogold-Silver Technique,Immunolabeling Technic,Immunolabeling Technique,Technic, Immunogold,Technic, Immunogold-Silver,Technic, Immunolabeling,Technics, Immunogold,Technics, Immunogold-Silver,Technics, Immunolabeling,Technique, Immunogold,Technique, Immunogold-Silver,Technique, Immunolabeling,Techniques, Immunogold,Techniques, Immunogold-Silver,Techniques, Immunolabeling
D007758 Ear, Inner The essential part of the hearing organ consists of two labyrinthine compartments: the bony labyrinthine and the membranous labyrinth. The bony labyrinth is a complex of three interconnecting cavities or spaces (COCHLEA; VESTIBULAR LABYRINTH; and SEMICIRCULAR CANALS) in the TEMPORAL BONE. Within the bony labyrinth lies the membranous labyrinth which is a complex of sacs and tubules (COCHLEAR DUCT; SACCULE AND UTRICLE; and SEMICIRCULAR DUCTS) forming a continuous space enclosed by EPITHELIUM and connective tissue. These spaces are filled with LABYRINTHINE FLUIDS of various compositions. Labyrinth,Bony Labyrinth,Ear, Internal,Inner Ear,Membranous Labyrinth,Bony Labyrinths,Ears, Inner,Ears, Internal,Inner Ears,Internal Ear,Internal Ears,Labyrinth, Bony,Labyrinth, Membranous,Labyrinths,Labyrinths, Bony,Labyrinths, Membranous,Membranous Labyrinths
D008297 Male Males
D008578 Meninges The three membranes that cover the BRAIN and the SPINAL CORD. They are the dura mater, the arachnoid, and the pia mater.
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D009361 Neoplasm Invasiveness Ability of neoplasms to infiltrate and actively destroy surrounding tissue. Invasiveness, Neoplasm,Neoplasm Invasion,Invasion, Neoplasm
D009367 Neoplasm Staging Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D002277 Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for "cancer." Carcinoma, Anaplastic,Carcinoma, Spindle-Cell,Carcinoma, Undifferentiated,Carcinomatosis,Epithelial Neoplasms, Malignant,Epithelioma,Epithelial Tumors, Malignant,Malignant Epithelial Neoplasms,Neoplasms, Malignant Epithelial,Anaplastic Carcinoma,Anaplastic Carcinomas,Carcinoma, Spindle Cell,Carcinomas,Carcinomatoses,Epithelial Neoplasm, Malignant,Epithelial Tumor, Malignant,Epitheliomas,Malignant Epithelial Neoplasm,Malignant Epithelial Tumor,Malignant Epithelial Tumors,Neoplasm, Malignant Epithelial,Spindle-Cell Carcinoma,Spindle-Cell Carcinomas,Tumor, Malignant Epithelial,Undifferentiated Carcinoma,Undifferentiated Carcinomas
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D004428 Ear Neoplasms Tumors or cancer of any part of the hearing and equilibrium system of the body (the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR). Auricular Cancer,Auricular Neoplasms,Cancer of Ear,Ear Cancer,Cancer of Ear Auricle,Cancer of the Ear,Neoplasms of Ear Auricle,Neoplasms, Auricular,Neoplasms, Ear,Auricular Cancers,Cancer, Auricular,Cancers, Auricular,Ear Auricle Cancer,Ear Auricle Cancers,Ear Auricle Neoplasm,Ear Auricle Neoplasms,Ear Neoplasm,Neoplasm, Ear

Related Publications

Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
Basal cell carcinoma of the external auditory meatus.
June 1984, Clinical otolaryngology and allied sciences,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
Squamous cell carcinoma of the external auditory meatus (canal).
September 1989, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
Primary carcinoma of the external auditory meatus.
January 1948, British medical journal,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
Bilateral carcinoma of the external auditory meatus.
February 1991, The Journal of laryngology and otology,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
[Spindle-cell thymoma (a histological and electron microscopic study)].
January 1978, Arkhiv patologii,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
[Bilateral primary carcinoma of the external auditory meatus].
May 2001, Nihon Jibiinkoka Gakkai kaiho,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
Carcinoma of the external auditory meatus and middle ear.
October 1984, Clinical otolaryngology and allied sciences,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
Spindle cell carcinoma of cornea and conjunctiva with pseudosarcomatous metaplasia. Light microscopic, electron microscopic and immunohistochemical findings in 2 patients.
May 1989, Chinese medical journal,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
[Carcinoma of the skin of the external auditory meatus].
January 2004, Acta chirurgica Iugoslavica,
Antonio Quaranta, and Paolo Berardi, and Domenico Piscitelli, and Maria Grazia Fiore, and Antonello Calace, and Leonardo Resta
[Basal squamous cell carcinoma of external auditory meatus: a case report].
March 2019, Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery,
Copied contents to your clipboard!