Biomaterial Database

Household transmission of vaccinia virus from contact with a military smallpox vaccinee--Illinois and Indiana, 2007. 2007

On March 7, 2007, the Chicago Department of Public Health and the University of Chicago Pediatric Infectious Disease Service and Infection Control Program notified CDC of a child with presumed eczema vaccinatum (EV), a life-threatening complication of vaccinia virus infection. This is the first reported EV case in the United States since 1988. This report summarizes the epidemiologic and environmental investigations conducted by local, state, and federal public health authorities in Illinois and Indiana to determine the source of exposure and to identify and monitor other persons at risk for vaccinia virus infection. This case highlights the need for clinicians to maintain a high index of suspicion when evaluating recently vaccinated patients and their family members with vesiculopustular rash.

UI	MeSH Term	Description	Entries
D007087	Illinois	State bounded on the north by Wisconsin, on the east by Lake Michigan, Indiana, and Kentucky, on the west by Missouri and Iowa, and on the south by Kentucky.
D007196	Indiana	State bounded on the north by Lake Michigan and Michigan, on the east by Ohio, on the south by Kentucky, and on the west by Illinois.
D008297	Male		Males
D008889	Military Personnel	Persons including soldiers involved with the armed forces.	Air Force Personnel,Armed Forces Personnel,Army Personnel,Coast Guard,Marines,Navy Personnel,Sailors,Soldiers,Submariners,Military,Force Personnel, Air,Personnel, Air Force,Personnel, Armed Forces,Personnel, Army,Personnel, Military,Personnel, Navy,Sailor,Soldier,Submariner
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004485	Eczema	A dermatitis characterized by a spongiotic tissue reaction pattern occurring as a reaction to many endogenous and exogenous agents.	Dermatitis, Eczematous,Eczematous Dermatitis
D005191	Family Characteristics	Size and composition of the family.	Family Size,Couples,Family Demography,Family Life Surveys,Family Size, Average,Family Size, Completed,Family Size, Desired,Family Size, Expected,Family Size, Ideal,Family and Household,Generations,Head of Household,Households,One-Person Household,Average Family Size,Average Family Sizes,Completed Family Size,Completed Family Sizes,Demography, Family,Desired Family Size,Desired Family Sizes,Expected Family Size,Expected Family Sizes,Family Characteristic,Family Demographies,Family Life Survey,Family Sizes,Family Sizes, Ideal,Household,Household Head,Household Heads,Household and Family,Household, One-Person,Ideal Family Size,Ideal Family Sizes,One Person Household,One-Person Households,Survey, Family Life
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012900	Smallpox Vaccine	A VACCINIA VIRUS vaccine used for immunization against SMALLPOX. It is now recommended only for laboratory workers exposed to SMALLPOX VIRUS. Certain countries continue to vaccinate those in the military service. Rare complications most often associated with older generation smallpox vaccines include VACCINIA, secondary bacterial infections, and ENCEPHALOMYELITIS. Because MONKEYPOX VIRUS and SMALLPOX VIRUS are both ORTHOPOXVIRUS and are closely related smallpox vaccines provide effective CROSS-PROTECTION against MPOX (MONKEYPOX) (https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html).	Monkey Pox Vaccine,Monkeypox Vaccine,Monkeypox and Smallpox Vaccine,Mpox Vaccine,Mpox and Smallpox Vaccine,Small Pox Vaccine,Smallpox and Monkeypox Vaccine,Smallpox and Mpox Vaccine,Vaccinia Vaccine,Vaccine, Monkey Pox,Vaccine, Monkeypox,Vaccine, Mpox,Vaccine, Small Pox,Vaccine, Smallpox,Vaccine, Vaccinia
D014615	Vaccinia	The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.	Vaccinias