-transparent.png){kind=logo}
One hundred and eighty patients with acute myocardial infarction (MI) were followed up. The patients were divided into 3 groups: (1) those receiving glyceryl trinitrate (GTN) (n = 43); (2) those on isosorbide dinitrate (ISDN) (n = 66); (3) those on isosorbide-5-mononitrate (IS-5-MN) (n = 71). In all the groups, the drugs were given by long-term continuous oligovolumic infusion. Following 24 hours of administration, 66.7, 47.3, and 17.1% increases in infusion rates were required in 74.4, 72.7, and 26.8% of the patients from Groups 1, 2, and 3, respectively. All the agents produced a pronounced antianginal effect and resulted in alleviated acute left ventricular failure. The in-hospital mortality rates were 16.2, 16.7, and 12.7% in Groups 1, 2, and 3, respectively. GTN, ISDN, and IS-5-MN caused adverse effects in 4.7, 18.2, and 2.8% of the patients from Groups 1, 2, and 3, respectively.
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
October 1987,
Clinical cardiology,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
January 1989,
Cor et vasa,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
March 1989,
Arquivos brasileiros de cardiologia,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
May 1984,
British journal of clinical pharmacology,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
September 1989,
International journal of clinical pharmacology, therapy, and toxicology,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
June 1985,
Ugeskrift for laeger,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
May 1971,
Circulation,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
June 1990,
The American journal of cardiology,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
July 1990,
European heart journal,
L B Lazebnik, and
S N Tereshchenko, and
A M Gendel'man
January 1987,
Cardiology,
