| D007328 |
Insulin |
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). |
Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin |
|
| D005227 |
Fatty Acids |
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed) |
Aliphatic Acid,Esterified Fatty Acid,Fatty Acid,Fatty Acids, Esterified,Fatty Acids, Saturated,Saturated Fatty Acid,Aliphatic Acids,Acid, Aliphatic,Acid, Esterified Fatty,Acid, Saturated Fatty,Esterified Fatty Acids,Fatty Acid, Esterified,Fatty Acid, Saturated,Saturated Fatty Acids |
|
| D000090943 |
Delta-5 Fatty Acid Desaturase |
A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2. |
Delta 5 Desaturase,Delta-5-FADase,Fatty Acid Delta-5-Desaturase,5 Desaturase, Delta,Acid Delta-5-Desaturase, Fatty,Delta 5 FADase,Delta-5-Desaturase, Fatty Acid,Desaturase, Delta 5,Fatty Acid Delta 5 Desaturase |
|
| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
|
| D013230 |
Stearoyl-CoA Desaturase |
An enzyme that catalyzes the formation of oleoyl-CoA, A, and water from stearoyl-CoA, AH2, and oxygen where AH2 is an unspecified hydrogen donor. |
Stearyl-CoA Desaturase,Stearate Desaturase,delta-9 Desaturase,Desaturase, Stearate,Desaturase, Stearoyl-CoA,Desaturase, Stearyl-CoA,Desaturase, delta-9,Stearoyl CoA Desaturase,Stearyl CoA Desaturase,delta 9 Desaturase |
|
| D014162 |
Transfection |
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES. |
Transfections |
|
| D017667 |
Adipocytes |
Cells in the body that store FATS, usually in the form of TRIGLYCERIDES. WHITE ADIPOCYTES are the predominant type and found mostly in the abdominal cavity and subcutaneous tissue. BROWN ADIPOCYTES are thermogenic cells that can be found in newborns of some species and hibernating mammals. |
Fat Cells,Lipocytes,Adipocyte,Cell, Fat,Cells, Fat,Fat Cell,Lipocyte |
|
| D044943 |
Fatty Acid Desaturases |
A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN. |
Acyl CoA Desaturase,Enoyl CoA Reductase,Fatty Acid Desaturase,Fatty Acid Desaturating Enzymes,Acyl CoA Desaturases,Enoyl CoA Reductases,Acid Desaturase, Fatty,CoA Desaturase, Acyl,CoA Reductase, Enoyl,Desaturase, Acyl CoA,Desaturase, Fatty Acid,Desaturases, Fatty Acid,Reductase, Enoyl CoA,Reductases, Enoyl CoA |
|
| D051379 |
Mice |
The common name for the genus Mus. |
Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus |
|
| D018955 |
CD36 Antigens |
Leukocyte differentiation antigens and major platelet membrane glycoproteins present on MONOCYTES; ENDOTHELIAL CELLS; PLATELETS; and mammary EPITHELIAL CELLS. They play major roles in CELL ADHESION; SIGNAL TRANSDUCTION; and regulation of angiogenesis. CD36 is a receptor for THROMBOSPONDINS and can act as a scavenger receptor that recognizes and transports oxidized LIPOPROTEINS and FATTY ACIDS. |
Antigens, CD36,OKM5 Antigen,Platelet Glycoprotein IV,Platelet Membrane Glycoprotein IIIb,Receptors, Thrombospondin,Scavenger Receptors, Class B, Type I,Thrombospondin Receptors,Adipocyte Membrane Protein p88,CD36 Antigen,CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor),CD36 Fatty Acid Transporter,CD36 Protein,FAT (Fatty Acid Translocase) - CD36 Antigen,GPIIIb Platelet Glycoprotein,GPIV Platelet Glycoprotein,Platelet Glycoprotein IIIb,Platelet Membrane Glycoprotein IV,SR-BI Protein,SR-BI Receptor,Thrombospondin Receptor,Antigen, CD36,Antigen, OKM5,Glycoprotein IIIb, Platelet,Glycoprotein IV, Platelet,Platelet Glycoprotein, GPIIIb,Platelet Glycoprotein, GPIV,Receptor, SR-BI,Receptor, Thrombospondin,SR BI Protein,SR BI Receptor |
|
-transparent.png){kind=logo}
