| D002454 |
Cell Differentiation |
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs. |
Differentiation, Cell,Cell Differentiations,Differentiations, Cell |
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| D005227 |
Fatty Acids |
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed) |
Aliphatic Acid,Esterified Fatty Acid,Fatty Acid,Fatty Acids, Esterified,Fatty Acids, Saturated,Saturated Fatty Acid,Aliphatic Acids,Acid, Aliphatic,Acid, Esterified Fatty,Acid, Saturated Fatty,Esterified Fatty Acids,Fatty Acid, Esterified,Fatty Acid, Saturated,Saturated Fatty Acids |
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| D000076084 |
Ubiquitin-Specific Peptidase 7 |
A ubiquitinyl hydrolase that deubiquitinates several proteins with critical roles in DNA REPAIR, cell growth, and survival, including TUMOR SUPPRESSOR PROTEIN P53; MDM-2 PROTEIN; and PTEN PHOSPHOHYDROLASE. It also stabilizes herpesvirus 1 trans-acting transcriptional protein VMW110 during HSV-1 infection, contributing to its function as a TRANS-ACTIVATOR. |
HAUSP Protein,Herpesvirus-Associated Ubiquitin-Specific Peptidase,USP7 Protein,Herpesvirus Associated Ubiquitin Specific Peptidase,Peptidase 7, Ubiquitin-Specific,Peptidase, Herpesvirus-Associated Ubiquitin-Specific,Ubiquitin Specific Peptidase 7,Ubiquitin-Specific Peptidase, Herpesvirus-Associated |
|
| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
|
| D014158 |
Transcription, Genetic |
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION. |
Genetic Transcription |
|
| D017667 |
Adipocytes |
Cells in the body that store FATS, usually in the form of TRIGLYCERIDES. WHITE ADIPOCYTES are the predominant type and found mostly in the abdominal cavity and subcutaneous tissue. BROWN ADIPOCYTES are thermogenic cells that can be found in newborns of some species and hibernating mammals. |
Fat Cells,Lipocytes,Adipocyte,Cell, Fat,Cells, Fat,Fat Cell,Lipocyte |
|
| D051379 |
Mice |
The common name for the genus Mus. |
Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus |
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| D051701 |
Activating Transcription Factor 4 |
An activating transcription factor that regulates the expression of a variety of GENES involved in amino acid metabolism and transport. It also interacts with HTLV-I transactivator protein. |
ATF4 Transcription Factor,Tax-Responsive Enhancer Element B67,Tax Responsive Enhancer Element B67,Transcription Factor, ATF4 |
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| D051780 |
Sterol Regulatory Element Binding Protein 1 |
A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING. |
Adipocyte Determination And Differentiation Factor 1,SRE-1 Binding Protein,SREBP-1a,SREBP-1c,SREBP1 Protein,Sterol Regulatory Element Binding Protein 1a,Sterol Regulatory Element Binding Protein 1c,Sterol Regulatory Element-Binding Protein 1,Transcription Factor ADD1,ADD1, Transcription Factor,SRE 1 Binding Protein,SREBP 1a,SREBP 1c |
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| D041721 |
3T3-L1 Cells |
A continuous cell line that is a substrain of SWISS 3T3 CELLS developed though clonal isolation. The mouse fibroblast cells undergo an adipose-like conversion as they move to a confluent and contact-inhibited state. |
3T3-L1,3T3 L1 Cells,3T3-L1 Cell,Cell, 3T3-L1,Cells, 3T3-L1 |
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